To draw reconstruction plans following major earthquakes, such as the Great East Japan Earthquake of 2011, it is necessary to quickly estimate the amount of disaster waste. To this end, remote sensing data is used, which affects all subsequent processing. However, the digital number of each pixel of the remote sensing data represents the average land cover conditions. That is, the information provided by a pixel should be represented as a one-pixel mixed class ('mixel') instead of a one-pixel single class. In previous papers, we had proposed a method of land cover classification using Thailand Earth Observation System data of a stricken area. The land cover classification results were in good agreement with a manually classified map which referenced the geological map and aerial photograph. However, to detect collapsed buildings, a minimum 2-m ground resolution is required. Therefore, we additionally proposed a method of land cover classification using RapidEye data. The ground resolution of RapidEye data was improved to 2-m from 6.5-m by the proposed method. These examination results suggested that the method is effective in the classification of land cover conditions using RapidEye data. Nevertheless, the disaster building domain was not yet estimated. In this paper, we therefore propose a method to estimate the disaster building domain using RapidEye data acquired before and after an earthquake. The effectiveness of this method is confirmed by evaluation results.