Abstract:Objective: to observe effect of combination of lithium and lamotrigine in treatment for Rapid-cycling bipolar disorder(RCBD). Method: We searched both MEDLINE, EMBASE, Cochrane Library in English and CBM, CNKI, WANFANG and CSSCI in Chinese to find literature from January 1 2000 to December 31, 2020 related to combination of lithium carbonate and lamotrigine for treatment of RCBD.Results: Five comparison studies, with 265 subjects of 131 cases in study group and 134 cases in control group met the inclusion crit… Show more
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