LAMMER Kinase Modulates Cell Cycle by Phosphorylating the MBF Repressor, Yox1, in
Schizosaccharomyces pombe
Kibum Park,
Joo-Yeon Lim,
Je-Hoon Kim
et al.
Abstract:Lkh1, a LAMMER kinase homolog in the fission yeast
Schizosaccharomyces pombe
, acts as a negative regulator of filamentous growth and flocculation. It is also involved in the response to oxidative stress. The
lkh1-
deletion mutant displays slower cell growth, shorter cell size, and abnormal DNA content compared to the wild type. These phenotypes suggest that Lkh1 controls cell size and cell cycle progression. When we performed microarray analysis using the
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