The precise dynamics of breakdown in pipe transition is a centuryold unresolved problem in fluid mechanics. We demonstrate that the abruptness and mysteriousness attributed to the Osborne Reynolds pipe transition can be partially resolved with a spatially developing direct simulation that carries weakly but finitely perturbed laminar inflow through gradual rather than abrupt transition arriving at the fully developed turbulent state. Our results with this approach show during transition the energy norms of such inlet perturbations grow exponentially rather than algebraically with axial distance. When inlet disturbance is located in the core region, helical vortex filaments evolve into large-scale reverse hairpin vortices. The interaction of these reverse hairpins among themselves or with the near-wall flow when they descend to the surface from the core produces small-scale hairpin packets, which leads to breakdown. When inlet disturbance is near the wall, certain quasi-spanwise structure is stretched into a Lambda vortex, and develops into a large-scale hairpin vortex. Small-scale hairpin packets emerge near the tip region of the large-scale hairpin vortex, and subsequently grow into a turbulent spot, which is itself a local concentration of small-scale hairpin vortices. This vortex dynamics is broadly analogous to that in the boundary layer bypass transition and in the secondary instability and breakdown stage of natural transition, suggesting the possibility of a partial unification. Under parabolic base flow the friction factor overshoots Moody's correlation. Plug base flow requires stronger inlet disturbance for transition. Accuracy of the results is demonstrated by comparing with analytical solutions before breakdown, and with fully developed turbulence measurements after the completion of transition.T he vast and expanding realm of fluid mechanics research on transition and turbulence can actually be traced back to a single point in history: the publication of Osborne Reynolds' 1883 pipe flow paper (1) in which the concept of Reynolds number was introduced. Given the historical, fundamental, and applied importance of the problem, it is ironic that the Osborne Reynolds pipe transition remains to this day "abrupt and mysterious" (2, 3).Significant progress has been made during the past decade, mostly concentrating on the detection of traveling wave (4, 5), and on the lifetime and reverse transition (relaminarization) of existing pipe flow turbulence produced by strong jet-in-crossflow type of blowing and suction (6, 7). Refs. 8 and 9 reported insightful relaminarization simulations using the axially periodic boundary condition.We tackle directly the Osborne Reynolds pipe transition problem with spatially developing direct numerical simulation (DNS). The disturbance energy growth rate with respect to axial distance, and how the friction factor and vortex structures develop during pipe transition with the distance, is currently unknown. We anticipate that weakly finite and localized disturbances introduced at ...