Laminar Necrosis and Hypoxic Damage of the Placenta: A Case-Control Study

Abstract

The aim of this study is to verify the role of laminar necrosis (LN) in the diagnosis of hypoxic damage of the placenta. This is a retrospective case-control study in which 50 cases with laminar necrosis were compared with 100 gestational age-matched controls without laminar necrosis in a 1:2 ratio. The parameters analyzed were: the presence of other placental lesions, obstetric characteristics and neonatal outcome. For each of the 50 cases, the area affected by the lesion was detected, and the lesions were classified into three groups based on the morphology and time of onset of the lesion in order to understand whether these characteristics of the lesion had a clinical-pathology. The results showed that including the search for LN among placental lesions generally examined is useful to guide the pathologist in the diagnosis of placental dysfunction of hypoxic origin.

Features of immunohistochemical markers of stem CELLS CD-117, CD-44 in female placentas on the background of chronic stress

“…Лише в поодиноких дослідженнях у вагітних із прееклампсією використано індуковані стовбурові клітини [27], які були синтезовані на структурних ДНК, що відповідають змінам на гіпоксію, пов'язану з дисфункцією плаценти [28].…”

“…Very isolated studies have used induced stem cells for treatment pregnant women with preeclampsia [27], which were synthesized on structural DNA corresponding to changes in hypoxia associated with placental dysfunction [28].…”