The flow structure and heat exchange in the zone of interference between an inclined shock and the surface of a flat plate are investigated experimentally and theoretically as functions of many parameters, the interference being studied in both the presence and the absence of bluntness of the leading edge. The experiments were carried out at Mach numbers M = 6, 8, and 10 and the Reynolds numbers Re L , calculated using the plate length L = 120 mm and the free-stream parameters, varied over the range from 0.24 · 10 6 to 1.31 · 10 6 . The bluntness radius of the leading edge of the plate, the intensity of the impinging shock, and its location with respect to the leading edge were varied. The numerical simulation was carried out by solving the complete two-dimensional Navier-Stokes equations and averaged Reynolds equations using the q-ω turbulence model. The laminar boundary layer became turbulent inside the separation zone induced by the shock. It is shown that the plate bluntness significantly reduces the heat exchange intensity in the interference zone, this effect intensifying with increase in the Mach number.