Lambda light chain deposition disease presenting as sicca syndrome

Hamidou, M.; Gires, C.; Moreau, Anne; Martin, Stéphane; Buzelin, F; Grolleau, J.Y.

doi:10.1002/art.1780400330

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Cited by 11 publications

(2 citation statements)

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“…It can present as a nephrotic syndrome, 4 retinal detachment, 5 cholestatic liver disease, 6 congestive cardiac failure, 7,8 arrhythmias, 9 neuropathy 10 or Sicca syndrome 11 One report of this deposition associated with marked systemic calcification is also noted in the literature. 12 Ig deposition in the myocardium is an uncommon but well described entity.…”

Section: Discussionmentioning

confidence: 98%

Cardiac nonamyloidotic immunoglobulin deposition disease

et al. 2006

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Section: Discussionmentioning

confidence: 98%

Cardiac nonamyloidotic immunoglobulin deposition disease

et al. 2006

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“…They can manifest as nephrotic syndrome [2], retina opacities [3], hepatic cholestasis [4], congestive heart failure [5,6], arrhythmias [7], neuropathy [8] or Sicca syndrome [9]. There are also some isolated cases where the deposition was associated with a marked systemic calcification [10].…”

Section: Introductionmentioning

confidence: 96%

Deposition-associated diseases related with a monoclonal compound

et al. 2007

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Up to 3% of adults over 50 years of age show a monoclonal peak values in blood or urine. Findings and prognosis will be distinct in view of the nature of this factor. In B-cell neoplasias (multiple myeloma, Waldeström macroglobulinaemia, chronic myeloid leukaemia and non-Hodgkin lymphoma) the clinical pattern is dominated by the systemic effects produced by the expansion of the malign clone; the monoclonal protein may result in hyperviscosity syndrome or renal damage. On the other hand, there are other less frequent processes called diseases associated to monoclonal components, where the main clinical manifestations and prognosis depend of the biological effects of the monoclonal protein. With reference to this last group, which is the objective of this revision, no bone lesions, anaemia or a greater tendency to infections usually occur when compared with the first group. Even so, there are some cases of interposition between both groups: for instance, type IgM immunoglobulin present in Waldeström macroglobulinaemia may have cold agglutinin activity, and in the case of multiple myeloma, the clone may secrete amyloidogenic light chains.

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Sialoses et sialadénoses

Astudillo¹

2020

Pathologies Des Glandes Parotides Et Submandibulaires De l'Adulte Et De l'Enfant

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Lambda light chain deposition disease presenting as sicca syndrome

Cited by 11 publications

References 6 publications

Cardiac nonamyloidotic immunoglobulin deposition disease

Cardiac nonamyloidotic immunoglobulin deposition disease

Deposition-associated diseases related with a monoclonal compound

Sialoses et sialadénoses

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