Lactose

Illanes, Andrés

doi:10.1016/b978-0-12-802724-0.00001-9

Cited by 14 publications

(1 citation statement)

References 252 publications

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“…In addition, the conventional STR, operated with batch mode does not enable the recycling of enzyme, an expensive item for the production of GOS 31. Therefore, the bottleneck of the production GOS in industrial scale is attributed to the cost of enzymes, operating cost of the system and complicated downstream purifying procedure 32.…”

Section: Introductionmentioning

confidence: 99%

Production of Galacto‐Oligosaccharides by Enzymatic Membrane Reactors Using Free β‐Galactosidase

Teng,

Nath,

Galambos

et al. 2024

Chemie Ingenieur Technik

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Prebiotic galacto‐oligosaccharides (GOSs) are synthesized by transgalactosylation of lactose using β‐galactosidases. Well‐established, large‐scale production of GOS is performed by stirred‐tank reactors (STR) operating in batch fashion. Main manufacturing expenses are attributed to enzyme purchase costs and the downstream operations required for subsequent enzyme inactivation and removal. In the last decades, several studies and patents have appeared on free enzyme membrane reactor (FEMR) as an economic alternative to STR due to enhanced enzyme recovery and reuse. In this review, we attempt to summarize the key design aspects, the catalytic performance and efficiency of FEMR compared to STR technology, and the main concerns related to stable product quality over long‐term operation.

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Section: Introductionmentioning

confidence: 99%

Production of Galacto‐Oligosaccharides by Enzymatic Membrane Reactors Using Free β‐Galactosidase

Teng,

Nath,

Galambos

et al. 2024

Chemie Ingenieur Technik

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Cheese Whey Permeate as a Precursor of Lactose-Free, Galactose-Rich Bioproducts: An Approach for Optimization and Application

Rivera Flores,

DeMarsh,

Fan

et al. 2023

Food Bioprocess Technol

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Under specific conditions of oxygen availability and lactose hydrolysis, Brettanomyces claussenii OYL-201 can convert glucose in dairy coproducts into ethanol, leaving the galactose almost untouched. This approach could be applied specifically to whey permeate (WP) to develop foods with low-glycemic loads and other potential health benefits. The aims of this research are to optimize the fermentation of WP by B. claussenii, to maximize the production of ethanol and galactose, and to characterize various products obtained with this approach. For this purpose, five fermentation factors were studied to determine their impacts on ethanol and galactose: temperature (20–40 °C), substrate concentration (5–15%TS), lactase enzyme/substrate ratio (0–40 IU/ g lactose), inoculation level (6–8 log cfu/mL), and time (6–30 days). Linear models, containing quadratic and interaction effects, were built for the optimization of both responses. Optimal levels were predicted for the maximum outputs of ethanol and galactose simultaneously, which utilized the following parameters: 15%TS, 37 IU / g lactose, 28 °C, 7.5 log cfu/mL, and 30 days, which together were predicted to produce 4.0%v/v ethanol and 51 g/L galactose in the final product. These parameters were applied to 18-L fermentations, and the fermentates were processed via distillation and freeze-drying. As a result, four product streams were obtained: a fermented product with 3.4%v/v ethanol and 56 g/L galactose, a 45%v/v ethanol distillate, a galactose-rich drink base (63 g/L), and a galactose-rich powder (55%w/w). These results demonstrate that it is possible to maximize the production of ethanol and galactose from WP and to develop novel, potentially functional bioproducts from this stream.

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Multivariate Classification of UHT Milk as to the Presence of Lactose Using Benchtop and Portable NIR Spectrometers

et al. 2018

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Lactose

Cited by 14 publications

References 252 publications

Production of Galacto‐Oligosaccharides by Enzymatic Membrane Reactors Using Free β‐Galactosidase

Production of Galacto‐Oligosaccharides by Enzymatic Membrane Reactors Using Free β‐Galactosidase

Cheese Whey Permeate as a Precursor of Lactose-Free, Galactose-Rich Bioproducts: An Approach for Optimization and Application

Multivariate Classification of UHT Milk as to the Presence of Lactose Using Benchtop and Portable NIR Spectrometers

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