A comparative study of serum uric acid, glucose, calcium and magnesium in eclampsia and normal pregnancy
Background: Preclampsia is associated with liver function abnormalities and renal function impairment.The objective of this study is to compare serum uric acid, glucose, calcium and magnesium in preclampsia with normal pregnancy. Materials and methods: Normal pregnant women and pre eclamptic women of age group 20-40 years were included. Serum magnesium, calcium, glucose, uric acid were analyzed. Results: Mean serum magnesium level in preclampsia (1.83 ± 0.21mg/dl) was lesser in comparison to normal pregnant women (2.03 ± 0.16 mg/dl). Serum calcium level was lower (8.10 ±0.56mg/dl) than control (9.59 ±0.62 mg/dl) with p<0.001. Uric acid, glucose and lactate dehydrogenase in preclamptic women was significantly higher than that in normal pregnant women (6.14 ± 0.85 vs.4.01 ± 0.62, p=<0.001), (94.17± 18.65 vs.86.34 ± 10.19, p=0.033) and ( 466.80 ± 97.29 vs. 194.22 ± 39.76, p=<0.001) respectively. Conclusion: There were significant changes in serum magnesium, uric acid, calcium, glucose, lactate dehydrogenase and total protein in pregnant women.