2011
DOI: 10.1007/s13224-011-0093-9
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Lactic Dehydrogenase: A Biochemical Marker for Preeclampsia–Eclampsia

Abstract: Objectives To correlate the severity of the disease, maternal and perinatal outcome with Lactic Dehydrogenase (LDH) levels in serum in patients of preeclampsia and eclampsia. Methods A prospective comparative study was conducted in the department of Obstetrics and Gynecology in the collaboration with department of Pathology, CSM Medical University, Lucknow. Out of 146 women studied, 39 were normal pregnant women, 35 were of mild preeclampsia, 36 of severe preeclampsia and 36 of eclampsia. The statistical analy… Show more

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Cited by 73 publications
(119 citation statements)
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“…Evaluation of LDH level during preclampsia can be useful in making decision, regarding the management strategies to improve the maternal and fetal outcome. 30 Similar type of finding was obtained by Jaiswar S P et al…”
Section: Discussionsupporting
confidence: 81%
“…Evaluation of LDH level during preclampsia can be useful in making decision, regarding the management strategies to improve the maternal and fetal outcome. 30 Similar type of finding was obtained by Jaiswar S P et al…”
Section: Discussionsupporting
confidence: 81%
“…[7][8][9][10] In the present study the LDH levels were significantly raised with the severity of the disease (P<0.001) and this was in accordance with the study done by Jaiswar SP et al, Qublan et al and Liggy A et al 7,8,11 The mean gestational age at the time of delivery in the present study was significantly less in patients with increasing LDH levels (P<0.05). This indicates increase in preterm deliveries in patients with higher LDH levels.…”
Section: Discussionsupporting
confidence: 91%
“…This will help in making decision, about the management guidelines for better maternal and fetal outcome. 7 Objectives of present study were to compare serum LDH levels in the normal pregnant women and in women with preeclampsia and eclampsia in ante-partum period and to study the association of maternal and perinatal outcomes with serum LDH levels.…”
Section: Introductionmentioning
confidence: 99%
“…The median LDH value was high in group1. 8 This is similar to the results obtained by S P Jaiswar et al, which showed 69.4% of patients with eclampsia had LDH >800 IU/L while only 19.4% had levels between 600 and 800 IU/L. They also observed that there is a significant rise in LDH levels with increasing severity of the disease.…”
Section: 3supporting
confidence: 90%