Lactic acid production by Bacillus coagulans—kinetic studies and optimization of culture medium for batch and continuous fermentations

Payot, T.; Chemaly, Z; Fick, Michel

doi:10.1016/s0141-0229(98)00098-2

Cited by 116 publications

(59 citation statements)

References 16 publications

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“…Based on the nature of the fermentation, lactic acid bacteria in general have been classified as homo-fermentative, resulting primarily in L-lactic acid as the only product, and hetero-fermentative, which produce small amounts of acetic acid and ethanol as byproducts. Major homo-fermentative products includes Lactococcus lactic [83], Lactobacillus delbrueckii [84]; Lactobacillus helveticus [85]; Lactobacillus casei [86], Bacillus subtilis [87], and Bacillus coagulans [88][89][90]. Similar to the VFA-producing bacteria, the Lactobacillus or Bacillus strains are rod-shaped bacteria that have a tendency to sporulate [80].…”

Section: Microbes Used For Lactic Acid Productionmentioning

confidence: 99%

“…Similar to the VFA-producing bacteria, the Lactobacillus or Bacillus strains are rod-shaped bacteria that have a tendency to sporulate [80]. A high lactate-producing bacterial strain such as B. coagulans showed as much as 92% lactic acid yield from sucrose [88]. Continuous fermentation of lignocellulosic biomass using an isolated B. coagulans strain resulted in lactic acid yield of 0.95 g/g biomass sugars with a productivity as high as 3.69 g/L/h at the optimum pH of 6 with a residence time as low as 6 h [90].…”

Section: Microbes Used For Lactic Acid Productionmentioning

confidence: 99%

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Biochemical Production and Separation of Carboxylic Acids for Biorefinery Applications

2017

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Carboxylic acids are traditionally produced from fossil fuels and have significant applications in the chemical, pharmaceutical, food, and fuel industries. Significant progress has been made in replacing such fossil fuel sources used for production of carboxylic acids with sustainable and renewable biomass resources. However, the merits and demerits of each carboxylic acid processing platform are dependent on the application of the final product in the industry. There are a number of studies that indicate that separation processes account for over 30% of the total processing costs in such processes. This review focuses on the sustainable processing of biomass resources to produce carboxylic acids. The primary focus of the review will be on a discussion of and comparison between existing biochemical processes for producing lower-chain fatty acids such as acetic-, propionic-, butyric-, and lactic acids. The significance of these acids stems from the recent progress in catalytic upgrading to produce biofuels apart from the current applications of the carboxylic acids in the food, pharmaceutical, and plastics sectors. A significant part of the review will discuss current state-of-art of techniques for separation and purification of these acids from fermentation broths for further downstream processing to produce high-value products.

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Section: Microbes Used For Lactic Acid Productionmentioning

confidence: 99%

Section: Microbes Used For Lactic Acid Productionmentioning

confidence: 99%

Biochemical Production and Separation of Carboxylic Acids for Biorefinery Applications

2017

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“…The e ect of pH on the speciÿc growth rate has been given by many workers (Yeh, Bajpai, & Iannotti, 1991, Roy, Goulet, & Leduy, 1987, Payot, Chemaly, & Fick, 1999, Fu & Mathews, 1999). An activity factor (a f ) is introduced to consider the e ect of actual pH of the system on the activity of the enzyme.…”

Section: Model Developmentmentioning

confidence: 99%

Intensification of enzymatic conversion of glucose to lactic acid by reactive extraction

Wasewar

Pangarkar

Heesink

et al. 2003

Chemical Engineering Science

108

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Lactic acid is an important commercial product and extracting this out of aqueous solution is a growing requirement in fermentation-based industries and recovery from waste streams. The design of an amine extraction process requires (i) equilibrium and (ii) kinetic data for the acid-amine (solvent) system used. Equilibria and kinetics for lactic acid extraction by Alamine 336 in octanol as a diluent have been determined and compared with other diluents studied earlier. An approach for extracting the lactic acid by a long-chain tertiary amine, which is in the dispersed phase as a liquid ion exchanger (LIX), is presented. A mathematical model for slurry phase reactor with glucose in the continuous aqueous phase, the amine with a diluent in the dispersed phase and the immobilized enzyme as the solid catalyst, has been developed using equilibrium and kinetic data for reactive extraction. E ects of various parameters a ecting the conversion of glucose have been discussed. The model has been solved for batch and semi-batch modes. It has been shown that the semi-batch mode yields approximately ÿve times higher productivity than batch mode. ?

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“…Apart from the large lactobacilli group, other bacteria, e.g. Bacillus coagulans [10], and filamentous fungi, especially Rhizopus oryzae [11], have also been used as production strains. In order to produce lactic acid from lucerne green juice (LGJ) in a technical facility, Lactobacillus paracasei 168 was used for developing a suitable fermentation technology.…”

Section: Introductionmentioning

confidence: 99%

Lactic Acid Production by Lactobacillus paracasei 168 in Discontinuous Fermentation Using Lucerne Green Juice as Nutrient Substitute

et al. 2010

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Lactic acid production by Bacillus coagulans—kinetic studies and optimization of culture medium for batch and continuous fermentations

Cited by 116 publications

References 16 publications

Biochemical Production and Separation of Carboxylic Acids for Biorefinery Applications

Biochemical Production and Separation of Carboxylic Acids for Biorefinery Applications

Intensification of enzymatic conversion of glucose to lactic acid by reactive extraction

Lactic Acid Production by Lactobacillus paracasei 168 in Discontinuous Fermentation Using Lucerne Green Juice as Nutrient Substitute

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