Lactate, pyruvate and blood gases in the carotid artery, jugular vein and pulmonary artery during submaximal exercise

Miller-Graber, Peggy A.; Lawrence, L.; Foreman, Jonathan H.; Smith, J. L.; Bump, K.D.

doi:10.1016/s0737-0806(88)80061-3

Cited by 9 publications

(2 citation statements)

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“…In this study, blood was collected from the jugular vein, and this blood may not be representative of the central circulation for some analytes such as pH, pyru‐vate concentration, and partial carbon dioxide and oxygen tensions 27 . LPO indices also might be affected by the site of sampling.…”

Section: Discussionmentioning

confidence: 99%

“…In this study, blood was collected from the jugular vein, and this blood may not be representative of the central circulation for some analytes such as pH, pyruvate concentration, and partial carbon dioxide and oxygen tensions. 27 LPO indices also might be affected by the site of sampling. However, the concentrations of other important biochemical parameters such as lactate do not differ between jugular vein and pulmonary artery samples, so we considered our data as representative for the central circulation.…”

Section: Discussionmentioning

confidence: 99%

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Biochemical and Antioxidant Changes in Plasma and Erythrocytes of Pentathlon Horses Before and After Exercise

Balogh

Gaál

Ribiczeyné

et al. 2001

Veterinary Clinical Pathol

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Physical exercise in the horse induces a series of normal physiological and biochemical adaptations. Increasing metabolism and oxygen uptake may induce oxidative stress in various organs. The aim of this study was to examine exercise-induced changes in some plasma and RBC biochemical and antioxidant variables in pentathlon horses. Blood samples were taken from 14 horses before, immediately after, and 24 hours after competing in two 1-minute runs of intense exercise over jumps. The peak intensity periods were preceded by a 20-minute warm-up and separated by a 20-minute break. The following plasma biochemical analytes were determined: total protein, uric acid, and lactate concentrations, and lactate dehydrogenase (LDH) and creatine kinase (CK) activities. Total antioxidant status (TAS) and the ferric reducing ability of plasma (FRAP) also were measured. Thiobarbituric acid-reactive substances (TBARS), reduced glutathione (GSH), and total protein concentrations, and glutathione peroxidase (GSHPx) and superoxide dismutase (SOD) activities were determined in RBC hemolysates. Significantly increased concentrations of total protein, lactate, and FRAP, and increased activities of CK and LDH were observed immediately postexercise compared with pre-exercise samples (P<0.05). All results returned to approximately initial values after 24 hours of rest. RBC GSH and TBARS concentrations did not change immediately after exercise, but decreased after 24 hours of rest (P<0.05). Plasma uric acid and FRAP values were positively correlated in a linear model (r = 0.78). In summary, the type of exercise applied in this study, which can be considered quite usual for pentathlon horses, caused detectable biochemical and lipid peroxidative changes in plasma and RBCs. FRAP and TAS values changed in opposite directions, indicating that when antioxidant capacity is assessed using different methods, highly different results may be obtained.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%