Lacrimal Gland Tumors and Simulating Lesions

Mafee, Mahmood F.; Edward, Deepak P.; Koeller, Kelly K.; Dorodi, Shervin

doi:10.1016/s0033-8389(05)70089-0

Cited by 64 publications

(31 citation statements)

References 40 publications

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“…7,11,13,15) Most cases of pleomorphic adenoma in a series of 40 cases of lacrimal gland tumors, with the exception of one case, exhibited slowly progressive painless swelling. 16) However, there were no cases of orbital bone destruction.…”

Section: Discussionmentioning

confidence: 99%

“…4,7,13) However, orbital bone destruction can occur even in cases of pseudotumor 3) or cholesterol granuloma. 6) If clinical evidence of intratumoral hemorrhage is found in a patient with an orbital tumor, malignancy should first be differentiated from other diseases such as cavernous angioma, 17,19) lymphangioma, 10) and cholesterol Unusual Progression of Lacrimal Pleomorphic Adenoma granuloma.…”

Section: Discussionmentioning

confidence: 99%

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Unusual Progression of Pleomorphic Adenoma of the Lacrimal Gland-Case Report-

Miyazaki

Yamasaki

Moritake

et al. 2005

Neurol. Med. Chir.(Tokyo)

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A 72-year-old female complained of acute pain on left eye movement followed by progressive exophthalmos. Neuroimaging revealed a large well-demarcated lesion consisting of solid and cystic parts, as well as bone destruction and hemorrhage, within the left orbital cavity. The preoperative diagnosis was pleomorphic adenoma with or without malignant transformation, or cavernous angioma. En bloc excision including adjacent tissues was planned to resolve the progressive symptoms and to obtain a histological diagnosis. The transcranial route was chosen since tumor invasion to the cranial base was possible. The histological diagnosis was pleomorphic adenoma. Pathological and preoperative radiological examinations indicated that repeated intratumoral hemorrhage had caused the orbital bone destruction and acute orbital pain. Neoplasms should be differentiated from a wide spectrum of other possible pathologies. Accurate clinical diagnosis of neoplasm in the orbital cavity is important for correct therapeutic management. Malignancy is generally suspected if painful and progressive signs and symptoms are associated with an orbital mass lesion. The present case suggests that pleomorphic adenoma should also be considered in the differential diagnosis. The therapeutic strategy for lacrimal gland tumors remains controversial, so a flexible management approach is required.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Unusual Progression of Pleomorphic Adenoma of the Lacrimal Gland-Case Report-

Miyazaki

Yamasaki

Moritake

et al. 2005

Neurol. Med. Chir.(Tokyo)

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“…On MRI, hypointense on T1WI, isointense on T2WI and moderate enhancement after contrast Gd-DTPA administration ( Figure 3). Our study shows regular/oval shaped well defined, mixed isodensity and mixed heterogeneous enhancement in pleomophic adenoma and irregular shaped, ill defined, isodensity, slightly heterogeneous enhancement and infiltrative adjustment tissues and bone erosion in adenoid cystic carcinoma (Figure 4) [29,30].…”

Section: Orbital Pleaomorphic Adenomamentioning

confidence: 98%

Valuation of Four-Quadrant Location Method in Diagnosis and Differential Diagnosis of the Orbital Tumor by Comparison Study Combining CT and MRI with Pathology

Akter¹,

Hasan²,

Sana³

et al. 2017

J Pain Relief

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Purpose: To valuate four-quadrant location method in diagnosis and differential diagnosis of the orbital tumor by comparison study combining CT and MRI with pathology. Materials and methods:Data of 87 patients (44 female and 43 males), aged 1 to 84 years were recruited in this study, including the computed tomography(CT), Magnetic resonance imaging (MRI), and histopathology diagnosis. All orbital tumors were verified radiologically and pathologically in the Hospital of Jinggangshan University from Sep-2008 to April-2016 patients underwent CT scanning (31 Conventional CT and 18 dynamic contrast enhancements CT) and 38 patients underwent MR Imaging (35 dynamic contrast enhancement MRI and 3 conventional MRI). The clinical data were retrieved from the medical record. We classified the orbital region according to four-quadrant and eight-space (FQES) division and traditional muscleconal division with center point of optic nerve. Results:Among the 87 cases of the orbital tumors, 70 cases (80.45%) were orbital benign tumors and 17 cases (19.54%) were malignant tumors. Regarding the location of the orbit, 41 lesions (47.12%) were in superolateral, 18 lesions (20.68%) were in inferolateral, 16 lesions (18.39%) were in inferomedial, 8 lesions (9.19%) were in superomedial, 3 lesions (3.44%) were in globe, 1 lesion (1.14%) was in optic nerve. The most common tumors are hemangiomas (total 36 cases: 12 in inferolateral, 8 in inferomedial, 9 in superolateral, 7 in superomedial) and 9 cases of pleomorphic adenoma were in superolateral, 9 cases of dermoid cyst ( 7 in superolateral and in 2 inferomedial), 5 cases of inflammatory pseudotumor (4 in superolateral and 1 in inferomedial), 7 cases of lymphoma (3 in superolateral, 2 in inferolateral and 2 in inferomedial ), 3 cases of adenoid cystic carcinoma in superolateral, 3 caese solitary fibrous tumor ( 2 in suprolateral and 1 in inferomedial), 3 cases lipoma (1 in superomedial, 1 in superolateral and 1 in inferolateral), 2 cases choroidal melanoma were in globe, 1 case of metastasis in superolateral, 1 case of meningioma in optic nerve, 1 case of malignant melanoma was in superolateral. The orbital tumors appeared in orbit with mostly regular, oval and rounds shape, well defined margin. The size ranged from 0.8 mm × 4.5 cm to 4.5 cm × 2.0 cm. The CT revealed iso-density in 22, slightly high-density in 15, mixed density in 6, low density in 5 and high density in 1 lesion. Among them, 18 were contrast enhancements. On T1WI image, the MRI revealed low signal intensity in 23 cases, slightly low signal in 4 cases, iso signal intensity in 7 case, high signal intensity in 3 cases, mixed signal intensity in 1 case on T2WI, it revealed high signal intensity in 23 cases, slightly high intensity in 7 cases, low signal intensity in 4 cases, iso signal intensity in 3 cases, mixed signal intensity in 1 case. Among them, 35 contrast enhancement MRI and 3 were non contrast MRI. Benign tumor was diagnosed in 70 patients, of them 34 were male and 36 were female, and the mean age was 45.19 ...

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“…Die pathologischen Veränderungen, die sich klinisch oft nur als unspezifische Vergrößerung der Drüse präsentieren, können in epitheliale und nicht epitheliale Läsionen eingeteilt werden [51]. Die häu-figsten sind die epithelialen Tumoren, die, vergleichbar mit den Tumoren der Speicheldrüsen, zur einen Hälfte benigne, gemischtzellige Tumoren, zur anderen Hälfte maligne Raumforderungen ausmachen [89].…”

Section: Erkrankungen Der Tränendrüseunclassified

“…Die Hauptvertreter der nicht epithelialen Veränderungen der Trä-nendrüse sind die entzündlichen Erkrankungen, wobei Die MRT zeigt neben diesen diagnostischen Kriterien das eher unspezifische Bild einer iso-bis hyperintensen Raumforderung, die mäßig bis kräftig Gadolinium anreichert und ebenso wenig wie die CT keine spezifische Differenzierung z.B. zu einer idiopathischen chronischen Entzündung (Abbildungen 27a und 27b) zulässt oder eine benigne Hyperplasie von einem malignen Lymphom zu trennen hilft [51].…”

Section: Erkrankungen Der Tränendrüseunclassified

Bildgebende Diagnostik von Orbitaerkrankungen

Müller‐Forell¹

2002

Klinische Neuroradiologie

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ZusammenfassungHintergrund: Dem Ophthalmologen sind mehr als 100 Erkrankungen der Orbita bekannt, die sich mit einer zum Teil verwirrenden Vielzahl von klinischen Symptomen präsentieren können. Da jedoch nur eine kleine Zahl dieser Erkrankungen der bildgebenden Diagnostik zugeführt werden muss, sind eine subtile Erfassung der klinischen Symptome und ihre Kommunikation unbedingte Voraussetzung für eine adäquate neuroradiologische Untersuchung. Die bildgebende Diagnostik der Orbita sollte grundsätzlich eine Darstellung in mindestens zwei Ebenen beinhalten. Die Zuordnung der pathologischen Veränderung zu einer der vier Hauptkompartimente der Orbita erleichtert die Differentialdiagnose erheblich und sollte am Beginn der diagnostischen Überlegungen stehen. Die subtile Erfassung der morphologischen Kriterien der jeweiligen Veränderung ist insbesondere in der CT-Diagnostik von größerer Bedeutung als eine zwanghafte Kontrastmittelgabe. Schlüsselwörter: Orbita · Differentialdiagnose · CT · MRT AbstractBackground: The orbit may be affected by more than 100 different clinical pathologies with a confusing number of symptoms. While only a small number of these diseases require diagnostic imaging, the evaluation and communication of clinical signs and symptoms play a crucial role in determining the appropriate neuroradiological investigation. Diagnostic imaging of the orbit, whether it should be ultrasound, CT or MRI, should consist of at least two directions. In order to facilitate differential diagnostic criteria the suspected and/or found pathology demand first a correct definition which of the four main orbital compartments is involved. Second the subtle definition of morphologic criteria of the pathologic process is more important than a mandatory application of contrast material for final diagnosis, especially on CT.

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Lacrimal Gland Tumors and Simulating Lesions

Cited by 64 publications

References 40 publications

Unusual Progression of Pleomorphic Adenoma of the Lacrimal Gland-Case Report-

Unusual Progression of Pleomorphic Adenoma of the Lacrimal Gland-Case Report-

Valuation of Four-Quadrant Location Method in Diagnosis and Differential Diagnosis of the Orbital Tumor by Comparison Study Combining CT and MRI with Pathology

Bildgebende Diagnostik von Orbitaerkrankungen

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