Lack of Vitamin D in Iraqi Children with Asthma

Al-Sharifi, Zainab A. Razak; Al-Ammar, Haider Abd Jabbar; Mahmood, Halla G.; Turki, Kismat Mohamed; Al-Karkhi, Ibrahim Isam

doi:10.13005/bpj/1085

Cited by 4 publications

(3 citation statements)

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“…Halasa et al (18) study in Jordan documented that low vitamin D is an important risk factor for high rates of bronchiolitis caused by respiratory syncytial virus among Jordanian children. In Iraq, it was found that vitamin D deficiency among children is associated with increase severity of asthma and increase the chance of lower respiratory tract infections among asthmatic children (19) .…”

Section: Discussion:-mentioning

confidence: 99%

Role of Vitamin D on Treatment of Bronchiolitis in Children

Falah¹,

FICMS²,

CABP³

2020

IJAR

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Background: Vitamin D plays a major role in growth and development of children. Optimal levels of vitamin D in first year of life are found to be preventive for lower respiratory tract infections. Aim of Study:To assess the effect of vitamin D supplementation on treatment of bronchiolitis. Patients and methods:This study is prospective follow up study conducted in Pediatric Wards of Al-Imamain Medical city in Baghdad through the period from 1 st of January, 2018 to 31 st of January, 2019 on convenient sample of 200 children with bronchiolitis divided into two group .group A include 98 children who were managed by traditional treatment of bronchiolitis (oxygen ,fluid ,frequent sucking of secretion ) and V.D supplementation (400 iu)daily and group B that include 102 children managed with traditional treatment only . The vital signs and hospital stay duration of children were assessed daily . Results: No significant differences were observed between two study groups regarding demographic, social, clinical and feeding characteristics. Also no significant differences were observed regarding respiratory rate at admission and at discharge. There was a significant difference regarding heart rate at discharge (p=0.05). A significant association was observed between children with vitamin D and shorter hospital stay duration (p<0.001).

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Section: Discussion:-mentioning

confidence: 99%

Role of Vitamin D on Treatment of Bronchiolitis in Children

Falah¹,

FICMS²,

CABP³

2020

IJAR

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“…The low serum vitamin D levels observed in asthmatic children compared with their healthy counterpart was in agreement with previous studies. 8,[20][21][22] This may be the result of short-term exposure to sun light and inadequate access to food and supplements. 23 The findings in this study of increased serum levels of PTH among the asthmatic children was consistent with the previous studies.…”

Section: Discussionmentioning

confidence: 99%

“…34 The finding of high prevalence of vitamin D deficiency obser ved among the asthmatic children was in agreement with the previous studies of. [18][19][20][21][22][23][24][25][26][27][28][29] that reported vitamin D deficiency among asthmatic children. The increased prevalence hypovitaminosis D could be due to the fact that families whose children happen to be asthmatic wanted to keep their children at home always for fear of an asthma attack, if they went outdoor or engaged in any physical activities.…”

Section: Discussionmentioning

confidence: 99%

Serum vitamin D status and biochemical parameters of asthmatic children in Sokoto Metropolis, North-western Nigeria

Yeldu¹,

Danjuma²,

Sulaiman³

et al. 2019

Asian J Med Sci

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Background: Asthma is a common chronic disorder of the airways that is complex and characterized by variable and recurring symptoms. It is characterized by the occurrence of bronchial hyper responsiveness, airflow obstruction and an underlying inflammation. Several studies have proposed the association of vitamin D with increased incidence of asthma symptoms. Aims and Objectives: This study aimed at determining the serum vitamin D status and biochemical parameters among asthmatic children in Sokoto-Nigeria. Materials and Methods: The study population consisted of 120 subjects including 80 asthmatic children and 40 age-and sex-matched apparently healthy controls from two tertiary Hospitals in Sokoto Metropolis. Serum vitamin D, calcium, parathyroid hormone (PTH), immunoglobulin E (IgE) and magnesium were measured using standard techniques. Results: Mean serum vitamin D and magnesium were significantly (p ˂ 0.05) lower, while serum PTH and IgE were significantly higher (p˂0.001) in asthmatic children than in controls. Vitamin D insufficiency was found to be prevalent among the asthmatic children. There was no significant relationship between the low level of vitamin D and asthma severity. Conclusion: This study observed that, hypovitaminosis D and hypomagnesaemia occurred among asthmatic children, and asthma was more prone in the younger children than in their older counterpart. It is recommended that in order to avoid or limit the rate of children having asthmatic episodes, vitamin D and magnesium supplements should be used in the management of asthmatic children.

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The serum level of vitamin D and prevalence of vitamin D deficiency among children with asthma in Asia and Africa: a systematic review and meta-analysis

Chanie,

Zhang,

Le Souef

2024

Arch Public Health

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Background Several studies on the serum level of vitamin D and the percentage of vitamin D deficiency in children with asthma have been conducted in Asia and Africa, but the results have been inconsistent and inconclusive, requiring a systematic review and meta-analysis to assess the strength of the evidence. Objective The objective of this review is to synthesize evidence on serum levels of vitamin D and the percentage of vitamin D deficiency among children with asthma in Asia and Africa. Methods To identify relevant articles, a comprehensive search was conducted across various databases and repositories such as PubMed, Google Scholar, Hinary, Web of Science, ResearchGate, as well as gray literature sources. The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were followed during the retrieval process. Data extraction was performed following a standardized format based on the JBI (Joanna Briggs Institute) data extraction guidelines. Microsoft Excel was utilized for data extraction, and subsequently, the data was exported to STATA 17 for further analysis. To assess the heterogeneity among the included studies, Cochrane Q-statistics and the I2 tests were employed. Publication bias was assessed using the Egger test and funnel plot. Result This meta-analysis investigated 33 articles encompassing a total of 3432 children diagnosed with asthma. The findings demonstrated that in low- or middle-income countries across Africa and Asia, children with asthma had an average serum vitamin D level of 21.9 ng/ml (95% confidence interval [CI]: 18.0–25.9 ng/ml), with 53.7% (95% CI: 40.5–66.9) experiencing vitamin D deficiency. Additionally, when considering the continent, children with asthma in Asia had an average serum vitamin D level of 18.5 ng/ml (95% CI: 13.8–23.3), while those in Africa had a level of 28.7 ng/ml (95% CI: 22.7–34.8). The analysis further explored different sub-group analyses. Depending on the study design, case–control studies yielded an average serum vitamin D level of 20.3 ng/ml (95% CI: 18.2–22.4), whereas cross-sectional studies resulted in 23.8 ng/ml (95% CI: 17.5–30.1). Based on publication year, studies published on or before 2015 had an average serum level of 21.0 ng/ml (95% CI: 18.0–24.0), while those published after 2015 had a level of 22.4 ng/ml (95% CI: 17.2–27.7). Moreover, when considering sample size, studies with 100 participants or less had an average serum level of 21.7 ng/ml (95% CI: 17.3–26.1), while studies with more than 100 participants had a level of 22.1 ng/ml (95% CI: 18.6–25.6). Conclusion Children with asthma in Asia and Africa were found to have low serum levels of vitamin D and a high percentage of vitamin D deficiency. This highlights the importance of early detection and monitoring of vitamin D levels in these children to prevent potential complications associated with vitamin D deficiency. Taking proactive measures to address and manage vitamin D deficiency is crucial for the well-being of children with asthma in these regions.

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Lack of Vitamin D in Iraqi Children with Asthma

Cited by 4 publications

References 0 publications

Role of Vitamin D on Treatment of Bronchiolitis in Children

Role of Vitamin D on Treatment of Bronchiolitis in Children

Serum vitamin D status and biochemical parameters of asthmatic children in Sokoto Metropolis, North-western Nigeria

The serum level of vitamin D and prevalence of vitamin D deficiency among children with asthma in Asia and Africa: a systematic review and meta-analysis

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