Lack of tonotopic organization of the auditory cortex in schizophrenia

Abstract

Background: Disorganization of tonotopy in the auditory cortex has been described in schizophrenia. Subjects with schizophrenia show little to no spatial organization of responses to different tone frequencies in the auditory cortex. Previous studies have called into question the use of MEG and the M100 response to assess tonotopy. This study seeks to replicate prior results of tonotopic disorganization in schizophrenia compared to healthy controls.