Lack of evidence of a role of XBP1 and PRDM1 polymorphisms in Spanish patients with immunoglobulin A deficiency

MSH5 is not a genetic predisposing factor for immunoglobulin A deficiency but marks the HLA-DRB1*0102 subgroup carrying susceptibility

“…If those haplotypes mark the same or distinct susceptibility factors remains uncertain [3]. Outside the HLA complex, several genes have been studied as possible susceptibility factors contributing to the disease [5][6][7][8][9][10][11][12][13], but very few of them rendered significant results [12,13].…”