Lack of correlation between blood group and HER-2 status in adenocarcinomas of the upper gastrointestinal tract

Hejna, Michael; Birner, Peter; Preusser, Matthias; Thallinger, Christiane; Worel, Nina; Asari, Reza; Dolak, Werner; Schmid, Rainer; Schoppmann, Sebastian F.; Raderer, Markus

doi:10.3892/mco.2013.181

Cited by 2 publications

(1 citation statement)

References 22 publications

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“…In a study of 100 upper gastrointestinal cancer patients, any relationship could not be established between human epidermal growth factor receptor 2 (HER2)-positivity and blood type. [23][24][25] Any relationship between blood type and HER2 positivity could not be found in breast cancer in another study. 24 Another study with 426 breast cancer patients detected no relationship between blood type and HER2, estrogen, and progesterone receptor positivity.…”

Section: Blood Type (N) Os Months (95% CImentioning

confidence: 87%

Association Between Blood Type and Epidermal Growth Factor Receptor Mutation Positivity in Lung Adenocarcinoma Patients

Gürbüz¹,

Akkuş²,

Karaalioğlu³

et al. 2021

J Oncol Sci

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Specific ABO blood group and Rh antigens are found to be associated with several malignancies and lung cancer. However, the relationship between blood type and Epidermal Growth Factor Receptor (EGFR) mutation in lung cancer remains poorly investigated. Material and Methods: In this retrospective case-control study, 105 EGFR mutation-positive and 169 EGFR mutation-negative lung adenocarcinoma patients were included. Baseline characteristics of the patients were determined. Odds ratios were calculated for the relationship of EGFR mutation positivity according to the ABO and Rh blood type. Overall survival difference according to the blood types was analyzed in metastatic patients that were diagnosed in the EGFR-mutant group. Results: There was no statistically significant increase observed in the relationship of EGFR mutation positivity for any of ABO and Rh types (OR and p-value, respectively; A

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Section: Blood Type (N) Os Months (95% CImentioning

confidence: 87%

Association Between Blood Type and Epidermal Growth Factor Receptor Mutation Positivity in Lung Adenocarcinoma Patients

Gürbüz¹,

Akkuş²,

Karaalioğlu³

et al. 2021

J Oncol Sci

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Distributions and prognostic effects of ABO/Rh blood groups in patients with HER2/neu positive gastric and gastroesophageal junction cancer

Dogan,

Gurbuz,

Aydin

et al. 2023

Journal of Cancer Research and Therapeutics

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Background: The aim of study was to look at ABO/Rh blood types frequency and prognostic significance in patients with HER2/neu positive gastric cancer. Methods: The study was designed retrospectively. Clinicopathological characteristics, treatment approaches, and the ABO/Rh blood groups features were noted. The ABO/Rh blood types for patients and healthy donors were compared by the Chi-square method. Results: The average age was 61 years. The average survival time was 17.9 months (13.2–22.5). ABO blood types frequencies were not similar between patients (25.9% O, 6.3% AB, 57.1% A, and 10.7% B) and control group (34.9% O, 7.9% AB, 41.9% A, and 15.3% B) (P = 0.01). Patients and controls had the same Rh factor distribution (P = 0.07). Conclusions: We showed that A blood group frequency was increased in patients with HER2/neu receptor-positive gastric cancer than in a healthy population. Also, we detected that the frequency of O blood type was decreased. ABO/Rh blood types were not linked with prognosis for overall survival.

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Lack of correlation between blood group and HER-2 status in adenocarcinomas of the upper gastrointestinal tract

Cited by 2 publications

References 22 publications

Association Between Blood Type and Epidermal Growth Factor Receptor Mutation Positivity in Lung Adenocarcinoma Patients

Association Between Blood Type and Epidermal Growth Factor Receptor Mutation Positivity in Lung Adenocarcinoma Patients

Distributions and prognostic effects of ABO/Rh blood groups in patients with HER2/neu positive gastric and gastroesophageal junction cancer

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