Lack of Association between IFNL3 Polymorphism and Human Papillomavirus Infection and Their Progression in HIV-Infected Women Receiving Antiretroviral Treatment
Abstract:Background: It has been reported that interferon-λ3 (IFNL3) might influence the pathogenesis and clearance of human papillomavirus (HPV) infection. The impact of IFNL3 singlenucleotide polymorphism (SNP) on HPV infection is currently unknown. The aim of this study was to investigate the association between variants in the IFNL3 region and HPV infection in women with human immunodeficiency virus (HIV) infection. Methods: A total of 236 HIV patients, including 65 HPV-negative and 171 HPV DNA-positive women, were… Show more
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