Labour productivity losses caused by premature death associated with hepatitis C in Spain

Abstract

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Value and innovation of direct-acting antivirals: long-term health outcomes of the strategic plan for the management of hepatitis C in Spain

“…In economic terms, this translates into increased indirect costs resulting from lost working hours as well as increased direct costs due to factors such as increased consumption of health resources (50). These costs may be added to the cost of premature deaths due to CHC, which has been estimated at €1,054 million over a period of three years (51). Only direct costs were incorporated in our analysis and any costs associated with the loss of productivity were excluded.…”

Treatment of patients waitlisted for liver transplant with all‐oral direct‐acting antivirals is a cost‐effective treatment strategy in the United States

“…Based on the consensus of a national panel of hepatologists, in the HCC model, 6 months of additional waitlist costs were added to the “LT from SVR” health state to simulate the delay to transplantation anticipated with improvement in clinical status. Treatment costs were based on RedBook pricing and 12 weeks of sofosbuvir/velpatasvir + ribavirin. Monitoring costs were based on Centers for Medicare and Medicaid pricing schedules, with resource use based on American Association for the Study of Liver Diseases guidelines and expert opinion…”

Cost-effectiveness analysis of chronic hepatitis C treatment in the prison population in Spain

“…Finalmente, si en vez de la perspectiva del SNS se hubiera usado la perspectiva social, considerando la pérdida de productividad de los pacientes con HCc, la opción de tratar hubiera supuesto mayores beneficios clínicos y económicos 41 . Por consiguiente, cabría esperar que los resultados del análisis aún fueran todavía más favorables para la opción de tratar.…”

“…Finally, if the social perspective had been used instead of that of the Spanish Health System and the loss of productivity in patients with CHC had been considered, the option of treating could be assumed to have greater clinical and economic benefits 41 . Therefore, one would expect the results of the analysis to further favour the option to treat.…”