Laboratory Testing for Substance Use Disorders

Dadiomov, David

doi:10.1007/978-3-030-33404-8_2

Cited by 3 publications

(5 citation statements)

References 11 publications

(11 reference statements)

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“…In addition, psychiatrists should be able to interpret laboratory investigations pertinent to substance use, such as liver function tests and urine drug metabolite tests. 46 Assessment skills to distinguish substance-induced psychiatric disorders from primary psychiatric disorders are essential for psychiatrists. Clinicians should be able to elicit a comprehensive history of both psychiatric symptoms and substance use to identify if a psychiatric disorder predated the substance use, persisted during periods of abstinence, or if symptoms are unrelated to periods of substance use, to determine if a co-occurring primary psychiatric condition is present.…”

Section: Screening Assessment and Diagnosismentioning

confidence: 99%

“…Des évidences de ce genre devraient provoquer une évaluation plus approfondie des critères des TUS du DSM-5-TR quand le patient peut participer (voir Tableau 1). En outre, les psychiatres devraient être capables d'interpréter les résultats de laboratoire qui relèvent de l'utilisation de substances, comme les tests de fonction hépatique et les tests urinaires de métabolites de drogues 46 Les compétences d'évaluation pour distinguer les troubles psychiatriques induits par des substances des troubles psychiatriques primaires sont essentielles pour les psychiatres. Les cliniciens devraient être en mesure d'obtenir des antécédents détaillés des symptômes psychiatriques et d'utilisation de substances pour identifier si un symptôme psychiatrique a précédé l'utilisation de substances, s'il a persisté durant les périodes d'abstinence, ou si les symptômes ne sont pas liés aux périodes d'utilisation de substances pour déterminer si une condition psychiatrique primaire concomitante est présente.…”

Section: Dépistage éValuation Et Diagnosticunclassified

“…In addition, psychiatrists should be able to interpret laboratory investigations pertinent to substance use, such as liver function tests and urine drug metabolite tests. 46…”

Section: A Review Of Key Clinical Concepts In Addiction Psychiatrymentioning

confidence: 99%

See 2 more Smart Citations

Training in Substance use Disorders, Part 1: Overview of Clinical Practice Recommendations

Bahji,

Crockford,

Brasch

et al. 2024

Can J Psychiatry

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Section: Screening Assessment and Diagnosismentioning

confidence: 99%

Section: Dépistage éValuation Et Diagnosticunclassified

See 1 more Smart Citation

Training in Substance use Disorders, Part 1: Overview of Clinical Practice Recommendations

Bahji,

Crockford,

Brasch

et al. 2024

Can J Psychiatry

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“…Most of these new substances are not detected by routine screening and confirmation methods, and due to the low doses of the highly potent drugs, the concentrations expected in the biological samples are in the low ng to pg/ml or ng to pg/g range, requiring extremely sensitive methods of analysis. 174 , 175 Routine screening is not undertaken in clinical practice as the results do not change outcome and are not available in a timeframe to change the outcome.…”

Section: Laboratory Testingmentioning

confidence: 99%

Synthetic opioids: a review and clinical update

Shafi

Berry

Sumnall

et al. 2022

Therapeutic Advances in Psychopharmacology

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The term ‘opioids’ refers to both the natural compounds (‘opiates’) which are extracted from the opium poppy plant ( Papaver somniferum) and their semi-synthetic and synthetic derivatives. They all possess relatively similar biochemical profiles and interact with the opioid receptors within the human body to produce a wide range of physiological effects. They have historically been used for medicinal purposes, their analgesic and sedative effects, and in the management of chronic and severe pain. They have also been used for non-medicinal and recreational purposes to produce feelings of relaxation, euphoria and well-being. Over the last decade, the emergence of an illegal market in new synthetic opioids has become a major global public health issue, associated with a substantial increase in unintentional overdoses and drug-related deaths. Synthetic opioids include fentanyl, its analogues and emerging non-fentanyl opioids. Their popularity relates to changes in criminal markets, pricing, potency, availability compared to classic opioids, ease of transport and use, rapid effect and lack of detection by conventional testing technologies. This article expands on our previous review on new psychoactive substances. We now provide a more in-depth review on synthetic opioids and explore the current challenges faced by people who use drugs, healthcare professionals, and global public health systems.

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“…Macrocytosis and elevated gamma-glutamyl transferase are valuable biological markers of alcohol consumption (Conigrave et al , 2003). Urine toxicology screening can help detect probable substance use, including cannabis, methamphetamine, cocaine, opioids and benzodiazepines (Dadiomov, 2020). The use of brain magnetic resonance imaging can aid in the diagnosis of Wernicke encephalopathy (Cerase et al , 2011).…”

Section: Approach To Substance Use Disorders In Older Adults With Neu...mentioning

confidence: 99%

Neurocognitive and substance use disorders in older adults: challenges and evidence

Agrawal

Sawaya

Ojeahere

et al. 2022

ADD

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Purpose This study aims to review the presentation of substance use disorders in older adults, how addiction intertwines with neurocognitive disorders and how to approach this vulnerable population. Design/methodology/approach Electronic data searches of PubMed, Medline and the Cochrane Library (years 2000–2021) were performed using the keywords “neurocognitive,” “dementia,” “substance use,” “addiction,” “older adults” and “elderly.” The authors, in consensus, selected pivotal studies and conducted a narrative synthesis of the findings. Findings Research about substance use disorders in older adults is limited, especially in those with superimposed neurocognitive disorders. Having dual diagnoses can make the identification and treatment of either condition challenging. Management should use a holistic multidisciplinary approach that involves medical professionals and caregivers. Originality/value This review highlights some of the intertwining aspects between substance use disorders and neurocognitive disorders in older adults. It provides a comprehensive summary of the available evidence on treatment in this population.

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Laboratory Testing for Substance Use Disorders

Cited by 3 publications

References 11 publications

Training in Substance use Disorders, Part 1: Overview of Clinical Practice Recommendations

Training in Substance use Disorders, Part 1: Overview of Clinical Practice Recommendations

Synthetic opioids: a review and clinical update

Neurocognitive and substance use disorders in older adults: challenges and evidence

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