Laboratory medicine in pandemic of COVID-19

Tandara, Leida; Filipi, Petra; Domić, Daniela Šupe; Krešić, Branka; Ivcic, Ivo; Stipić, Sanda Stojanović; Rubić, Žana; Tandara, Marijan

doi:10.11613/bm.2022.020501

Cited by 3 publications

(3 citation statements)

References 83 publications

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“…Because of neurological involvement, various biological markers can detect neuroinflammation and damage. In addition to the inflammatory and coagulopathy markers mentioned in other sections, these indicators can be beneficial: antiphospholipid antibodies, fibrillary acidic protein (GFAP), neurofilament light polypeptide, tau, S100B calcium-binding protein, and NSE (33).…”

Section: Metabolic Functionsmentioning

confidence: 99%

Radiological and Biochemical Findings of COVID-19

Sevgi¹,

Tahtasakal²

2022

csmedj

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Coronavirus disease-2019 (COVID-19) is a new COVID-19 that causes various health and safety concerns and socioeconomic difficulties worldwide. Early and accurate diagnosis, isolation, and management are critical public health concerns. Real-time reverse transcription polymerase chain reaction (RT-PCR) of viral nucleic acids was the reference in diagnosing COVID-19. In addition to RT-PCR, serological tests based on antibodies tested against severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) have been used for diagnosis and epidemiological research.In cases where the reference tests are negative, radiological imaging guides the diagnosis. Chest radiography and thoracic computed tomography (CT) are the most commonly used radiological methods in imaging for COVID-19. Chest radiography and CT play a critical role in diagnosing, following, and staging pneumonia. However, it can also evaluate the progression of the disease, prognosis prediction, and treatment follow-up. The clinical forms of COVID-19 can range from asymptomatic infection to severe pneumonia. Biochemical findings vary in patients with different clinical forms. Therefore, biochemical parameters help diagnose the disease, determine disease severity, and predict clinical outcomes. SARS-CoV-2 is present in many tissues, including the endothelium, liver, and kidney. It can also progress with multiorgan involvement. Among the biochemical parameters, those showing organ damage play a significant role.

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Section: Metabolic Functionsmentioning

confidence: 99%

Radiological and Biochemical Findings of COVID-19

Sevgi¹,

Tahtasakal²

2022

csmedj

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“…The need for continuous training to adapt to evolving testing methodologies and technologies became evident, emphasizing the necessity for ongoing professional development in the clinical laboratory setting. 5 Clinical laboratories have played a pivotal role in the global response to the COVID-19 pandemic, serving as the backbone of diagnostic efforts, monitoring, and research initiatives. From the early stages of the pandemic, these laboratories have been on the front lines, contributing significantly to understanding, detecting, and managing the virus.…”

Section: Introductionmentioning

confidence: 99%

“…9 Through molecular biology techniques, serological assays, and genomic analyses, laboratories have contributed valuable insights into the virus's behavior, the development of immunity, and the emergence of variants. 5 This research has informed public health strategies, vaccine development, and therapeutic interventions.…”

Section: Introductionmentioning

confidence: 99%

Clinical laboratory strategies for managing pandemic outbreaks

Alotaibi,

Alsoor,

Alnajrani

et al. 2024

Int J Community Med Public Health

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This review article comprehensively examines clinical laboratory strategies for managing pandemic outbreaks, with a particular focus on lessons learned from the COVID-19 pandemic. Drawing upon an extensive analysis of existing literature from databases such as PubMed, Web of Science, and Cochrane, as well as manual searches on Google Scholar, the study aims to provide insights into key aspects of pandemic preparedness and response. The literature review encompasses diverse combinations of medical terminology, emphasizing the role and response of clinical laboratories during pandemics. The primary focus areas include rapid test development and deployment, increased testing capacity, sample collection, and transportation protocols, data management, personnel safety, resource allocation, adaptability, and quality control measures. The inclusion of articles in this study adheres to rigorous criteria, ensuring a thorough and robust review process. The findings highlight the critical importance of rapid and accurate diagnostic testing, especially in the early stages of a pandemic, to facilitate timely interventions and containment. Efficient sample collection and transportation systems are crucial for maintaining the integrity of specimens, while advanced data management and reporting systems contribute to informed decision-making. Adaptability and flexibility are identified as indispensable traits for navigating the dynamic challenges of a pandemic, and stringent quality control measures are foundational for upholding the accuracy of diagnostic testing. The review underscores the collaborative efforts needed among clinical laboratories, public health agencies, and research institutions to strengthen global pandemic preparedness and response strategies.

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Digital and Computational Pathology Are Pathologists’ Physician Extenders

Schukow,

Allen

2024

Archives of Pathology &Amp; Laboratory Medicine

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Laboratory medicine in pandemic of COVID-19

Cited by 3 publications

References 83 publications

Radiological and Biochemical Findings of COVID-19

Radiological and Biochemical Findings of COVID-19

Clinical laboratory strategies for managing pandemic outbreaks

Digital and Computational Pathology Are Pathologists’ Physician Extenders

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