Laboratory Medicine and Diagnostic Pathology

Muzyka, Brian C.; Christie, John L.; Collins, Bobby

doi:10.1002/9781119597797.ch28

Cited by 1 publication

(1 citation statement)

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“…The diagnosis of inflammation in AD is a process involving many branches of medicine, including laboratory medicine, immunochemistry, clinical biochemistry, clinical immunology, hematology, anatomy, histology, and pathomorphology. It can be divided into two basic parts: basic or early, which includes basic laboratory tests often performed routinely by many patients and specialists, or late, which may include the following diagnostics: immunological, including flow cytometry, radiological and imaging diagnostics, with brain imaging of AD patients and pathological diagnostics, which include, among others immunohistochemical reactions and anatomopathological diagnostics, autopsies performed after the patient’s death [ 123 ]. Laboratory medicine plays a very important role in the process of diagnosing inflammation and AD itself at an early stage of development [ 124 ].…”

Section: Diagnostics Of the Inflammatory Process In Admentioning

confidence: 99%

Inflammatory Processes in Alzheimer’s Disease—Pathomechanism, Diagnosis and Treatment: A Review

Twarowski

Herbet

2023

IJMS

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Alzheimer’s disease is one of the most commonly diagnosed cases of senile dementia in the world. It is an incurable process, most often leading to death. This disease is multifactorial, and one factor of this is inflammation. Numerous mediators secreted by inflammatory cells can cause neuronal degeneration. Neuritis may coexist with other mechanisms of Alzheimer’s disease, contributing to disease progression, and may also directly underlie AD. Although much has been established about the inflammatory processes in the pathogenesis of AD, many aspects remain unexplained. The work is devoted in particular to the pathomechanism of inflammation and its role in diagnosis and treatment. An in-depth and detailed understanding of the pathomechanism of neuroinflammation in Alzheimer’s disease may help in the development of diagnostic methods for early diagnosis and may contribute to the development of new therapeutic strategies for the disease.

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Section: Diagnostics Of the Inflammatory Process In Admentioning

confidence: 99%