Laboratory intercomparison study on the analysis of short-chain chlorinated paraffins in an extract of industrial soil

Pellizzato, Francesca; Ricci, Marina; Held, Andrea; Emons, Hendrik; Böhmer, W.; Geiß, Sabine; Iozza, Saverio; Mais, Silvio; Petersen, Malte; Lepom, Peter

doi:10.1016/j.trac.2009.05.002

Cited by 33 publications

(30 citation statements)

References 13 publications

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“…For field samples with a complex matrix, such as sewage sludge, the difference of up to a factor of 4.4 for SCCP concentrations and 16 for MCCP concentrations between the APCI-qTOF-HRMS and the GC/ECNI-HRMS based concentrations is within deviations observed in previous interlaboratory comparison studies. Concentrations differing by more than an order of magnitude between laboratories have been reported for complex samples such as soil 34 or fish. 35,36 For the urban air samples with less matrix interferences but also with considerably lower concentrations of CPs in the injected extracts, the difference in concentrations of CPs by a factor of 0.7−2.8 between the two analytical methods is small.…”

Section: Analytical Chemistrymentioning

confidence: 99%

Fast Quantification of Chlorinated Paraffins in Environmental Samples by Direct Injection High-Resolution Mass Spectrometry with Pattern Deconvolution

et al. 2015

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Chlorinated paraffins (CPs) are high production volume chemicals, but data about their environmental fate are scarce. CP mixtures composed of thousands of isomers represent a major challenge for quantification at low levels in environmental samples. Here, we present a novel analytical method for analysis of short-chain, medium-chain, and long-chain CPs in a single injection, that also yields information about congener group pattern. Our detection method is based on direct injection into an atmospheric pressure chemical ionization source operated in negative ion mode under chlorine-enhanced conditions, followed by quadrupole time-of-flight high-resolution mass spectrometry (APCI-qTOF-HRMS) operated in full-scan mode. A mathematical algorithm is applied to deconvolute the CP patterns in the analyzed samples into a linear combination of patterns of technical CP mixtures and to quantify CPs using technical mixtures as external calibration standards. For CP mixtures with known composition, the new method provided concentrations that were within a factor of 1.2 of the target value. Accuracies for CPs spiked to sediment and fish extracts were between 91% and 123%. Concentrations determined in unspiked field samples were within a factor of 5 for short-chain CPs and a factor of 16 for medium-chain CPs of results obtained with an independent method based on gas chromatography/electron capture negative ionization high-resolution mass spectrometry (GC/ECNI-HRMS). The presented APCI-qTOF-HRMS pattern deconvolution method is an interesting alternative for CP analysis in environmental samples. It is particularly sensitive for medium- and long-chain CPs and has the advantage of being extremely fast (instrumental analysis time, less than 1 min).

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Section: Analytical Chemistrymentioning

confidence: 99%

Fast Quantification of Chlorinated Paraffins in Environmental Samples by Direct Injection High-Resolution Mass Spectrometry with Pattern Deconvolution

et al. 2015

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“…Of all the CP mixtures, SCCPs tend to behave in a similar way to persistent organic pollutants (POPs), leading to some countries and organizations to impose regulation on the production and use of these compounds (Pellizzato et al, 2009). Because of their persistence (Iozza et al, 2008), toxicity (Cooley et al, 2001;Warnasuriya et al, 2010), bioaccumulation (Fisk et al, 1996;Houde et al, 2008;Zeng et al, 2011b) and potential for long-range transport abilities (Tomy et al, 1999), SCCPs have been listed as POP candidate by the Stockholm Convention.…”

Section: Introductionmentioning

confidence: 99%

Levels and distribution patterns of short chain chlorinated paraffins in sewage sludge of wastewater treatment plants in China

Zeng

Wang

Ruan

et al. 2012

Environmental Pollution

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a b s t r a c tShort chain chlorinated paraffins (SCCPs) are listed as persistent organic pollutant candidates in the Stockholm Convention and are receiving more and more attentions worldwide. In general, concentrations of contaminants in sewage sludge can give an important indication on their pollution levels at a local/regional basis. In this study, SCCPs were investigated in sewage sludge samples collected from 52 wastewater treatment plants in China. Concentrations of total SCCPs (SSCCPs) in sludge were in the range of 0.80e52.7 mg/g dry weight (dw), with a mean value of 10.7 mg/g dw. Most of SCCPs in the sludge samples showed a similar congener distribution patterns, and C 11 and Cl 7,8 were identified as the dominant carbon and chlorine congener groups. Significant linear relationships were found among different SCCP congener groups (r 2 ! 0.9). High concentrations of SCCPs in sewage sludge imply thatSCCPs are widely present in China.

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“…The most common analytical procedures include attempts to increase selectivity by removing potentially interfering compounds as part of the clean-up process and apply gas chromatography (GC) in combination with high-resolution mass spectrometry(MS), or low-resolution MS (LRMS) (Tomy et al, 1997;Reth and Oehme, 2004). An interlaboratory test gave coefficients of variations >200% for shortchained chlorinated paraffin determination, confirming the need for further method development and consolidation (Pellizzato et al, 2009). An interlaboratory test gave coefficients of variations >200% for shortchained chlorinated paraffin determination, confirming the need for further method development and consolidation (Pellizzato et al, 2009).…”

Section: Examples Of Hydrophobic Contaminantsmentioning

confidence: 99%

How to Improve Exposure Assessment

Vorkamp¹,

McGeer²

2015

Aquatic Ecotoxicology

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Laboratory intercomparison study on the analysis of short-chain chlorinated paraffins in an extract of industrial soil

Cited by 33 publications

References 13 publications

Fast Quantification of Chlorinated Paraffins in Environmental Samples by Direct Injection High-Resolution Mass Spectrometry with Pattern Deconvolution

Fast Quantification of Chlorinated Paraffins in Environmental Samples by Direct Injection High-Resolution Mass Spectrometry with Pattern Deconvolution

Levels and distribution patterns of short chain chlorinated paraffins in sewage sludge of wastewater treatment plants in China

How to Improve Exposure Assessment

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