Laboratory evaluation of insect growth regulators against several species of anopheline mosquitoes

Kawada, Hiroyuki; Shono, Yoshinori; Ito, Takaaki; Abe, Yasuo

doi:10.7601/mez.44.349

Cited by 23 publications

(22 citation statements)

References 3 publications

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“…The estimated emergence inhibition rates from the dose–response tests were four times higher than those previously reported by Kawada and his colleagues [65] for An. gambiae, but within the range of rates estimated for Culex and Aedes species [66-70].…”

Section: Discussioncontrasting

confidence: 58%

Dose–response tests and semi-field evaluation of lethal and sub-lethal effects of slow release pyriproxyfen granules (Sumilarv®0.5G) for the control of the malaria vectors Anopheles gambiae sensu lato

Mbare

Lindsay

Fillinger

2013

Malar J

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BackgroundRecently research has shown that larviciding can be an effective tool for integrated malaria vector control. Nevertheless, the uptake of this intervention has been hampered by the need to re-apply larvicides frequently. There is a need to explore persistent, environmentally friendly larvicides for malaria vector control to reduce intervention efforts and costs by reducing the frequency of application. In this study, the efficacy of a 0.5% pyriproxyfen granule (Surmilarv®0.5G, Sumitomo Chemicals) was assessed for the control of Anopheles gambiae sensu stricto and Anopheles arabiensis, the major malaria vectors in sub-Saharan Africa.MethodsDose–response and standardized field tests were implemented following standard procedures of the World Health Organization’s Pesticide Evaluation Scheme to determine: (i) the susceptibility of vectors to this formulation; (ii) the residual activity and appropriate retreatment schedule for field application; and, (iii) sub-lethal impacts on the number and viability of eggs laid by adults after exposure to Sumilarv®0.5G during larval development.ResultsAnopheles gambiae s.s. and An. arabiensis were highly susceptible to Sumilarv®0.5G. Estimated emergence inhibition (EI) values were very low and similar for both species. The minimum dosage that completely inhibited adult emergence was between 0.01-0.03 parts per million (ppm) active ingredient (ai). Compared to the untreated control, an application of 0.018 ppm ai prevented 85% (95% confidence interval (CI) 82%-88%) of adult emergence over six weeks under standardized field conditions. A fivefold increase in dosage of 0.09 ppm ai prevented 97% (95% CI 94%-98%) emergence. Significant sub-lethal effects were observed in the standardized field tests. Female An. gambiae s.s. that were exposed to 0.018 ppm ai as larvae laid 47% less eggs, and females exposed to 0.09 ppm ai laid 74% less eggs than females that were unexposed to the treatment. Furthermore, 77% of eggs laid by females exposed to 0.018 ppm ai failed to hatch, whilst 98% of eggs laid by females exposed to 0.09 ppm ai did not hatch.ConclusionAnopheles gambiae s.s. and An. arabiensis are highly susceptible to Sumilarv®0.5G at very low dosages. The persistence of this granule formulation in treated habitats under standardized field conditions and its sub-lethal impact, reducing the number of viable eggs from adults emerging from treated ponds, enhances its potential as malaria vector control tool. These unique properties warrant further field testing to determine its suitability for inclusion in malaria vector control programmes.

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Section: Discussioncontrasting

confidence: 58%

Dose–response tests and semi-field evaluation of lethal and sub-lethal effects of slow release pyriproxyfen granules (Sumilarv®0.5G) for the control of the malaria vectors Anopheles gambiae sensu lato

Mbare

Lindsay

Fillinger

2013

Malar J

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“…The obtained data indicated that IGR Dudim (diflubenzuron) proved to have a delayed effect on C. pipiens larvae for the first 72hr after treatment. The obtained findings are in agreement with a previous study (Kawada et al, 1993) that discussed the larvicidal efficacy of IGR Dudim (diflubenzuron) on anopheline mosquitoes (A. sergenti, gambiae, albimanus). In all species, no cross resistance between IGRs and the other kinds of insecticides, such as organophosphate, organochlorine, carbamate and pyrethroid, was observed.…”

Section: Susceptibility Of C Pipiens To Some Control Agentssupporting

confidence: 83%

Toxicity and Joint Toxic Action of Some Control Agents on Culex pipiens L. Larvae

2010

Alexandria Science Exchange Journal: An International Quarterly

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The present study aimed to assess and to evaluate some of the sustainable and safe measures against Culex pipiens mosquito larva that can be implemented in areas at risk of contacting elephantiasis. The joint toxic action of these control measures was also studied. Data showed that Deltamethrin (LC 50 =0.021ppm) was more toxic than Bacillus thurengiensis var. israelensis, diflubenzuron, Finally, the use of some binary mixtures of the tested control measures can achieve better control, reduce control cost and induce lesser environmental pollution.

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“…34,45 The study by Kawada et al 45 used an emulsifiable concentrate (5%) formulation, while the present study used a granular formulation. Moreover, in the present study, the plastic bowls used during the bioassays were found to have retained high larvicide amounts leading to a higher residual effect relative to the aluminium bowls used by Kawada et al 45 Plastic materials are known to retain substantial amounts of active ingredient and to release it slowly, which could explain the higher emergence inhibition found in this study at all doses used. 36,37,48 Our experiments have shown that Sumilarv 0.5G is effective at low active ingredient concentrations.…”

Section: Experimental Weeksmentioning

confidence: 87%

Biological Activity of Sumilarv 0.5G against Anopheles gambiae sensu stricto and Anopheles arabiensis in Northern Tanzania

Kweka

Mahande

Msangi

et al. 2019

EASci

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Background: Sumilarv 0.5G (Sumitomo Chemical Co., Ltd., Tokyo, Japan) is a granular insecticide developed for the control of mosquito and fly aquatic stages. The active ingredient is pyriproxyfen (4-phenoxyphenyl (RS)-2-(2 – pyridyloxy) propyl ether), a juvenile hormone analogue that acts as an insect growth regulator. Sumilarv 0.5G functions by inhibition of adult emergence from pupae. In this study, the Tropical Pesticides Research Institute in Tanzania carried out laboratory, semifield, and full-field evaluation on a new candidate of pupicide, Sumilarv 0.5G. The present study, therefore, sought to test the bioefficacy of Sumilarv 0.5G in laboratory, semifield, and full-field conditions in Mabogini, northern Tanzania. Methods: Standard World Health Organization laboratory bioefficacy evaluations of Sumilarv 0.5G and untreated microcosms were prepared and monitored for inhibition of the larvae introduced to the habitats, while field plots were monitored for 5 weeks after the introduction of Sumilarv 0.5G using manufacturer-recommended doses. Results: Sumilarv 0.5G biolarvicide was highly efficacious in its pupicidal effect, with an adult emergence inhibition rate of up to 90% in all conditions. In both laboratory and semifield experiments, the emergence inhibition was dose-dependent, with the lowest adult emergence being recorded in association with the highest Sumilarv 0.5G dose of 0.03 ppm of active ingredient. Under field conditions, the application rate recommended by the manufacturer – 5 mg ai per m2 – reduced the adult emergence rate by 90% to 96% for up to 5 weeks. Conclusion: We demonstrated the long-lasting biological activity of Sumilarv 0.5G under field conditions. Notably, the field efficacy was attained using the recommended dose of 5 mg per m2, thus making it economical to apply this product, which is capable of inhibiting mosquito productivity in natural habitats for longer periods than achieved by existing products, the efficacy of which is usually about 1 week.

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Laboratory evaluation of insect growth regulators against several species of anopheline mosquitoes

Cited by 23 publications

References 3 publications

Dose–response tests and semi-field evaluation of lethal and sub-lethal effects of slow release pyriproxyfen granules (Sumilarv®0.5G) for the control of the malaria vectors Anopheles gambiae sensu lato

Dose–response tests and semi-field evaluation of lethal and sub-lethal effects of slow release pyriproxyfen granules (Sumilarv®0.5G) for the control of the malaria vectors Anopheles gambiae sensu lato

Toxicity and Joint Toxic Action of Some Control Agents on Culex pipiens L. Larvae

Biological Activity of Sumilarv 0.5G against Anopheles gambiae sensu stricto and Anopheles arabiensis in Northern Tanzania

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