2020
DOI: 10.1016/j.jiph.2020.06.005
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Laboratory diagnosis of SARS-CoV-2 - A review of current methods

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Cited by 115 publications
(114 citation statements)
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“…At present, with no specific therapeutic interventions or vaccines, COVID-19 has continued to cause a human and severe economic disruption affecting millions of people [ 6 ]. The disease pandemic and mortality showed the necessity for accurate and convenient approaches to diagnose, treat, and therapeutically monitor respiratory viral infections [ 7 , 8 ]. Several efforts have combined to rapidly develop a treatment and/or a vaccine to overcome the COVID-19 [ 9 ].…”
Section: Introductionmentioning
confidence: 99%
“…At present, with no specific therapeutic interventions or vaccines, COVID-19 has continued to cause a human and severe economic disruption affecting millions of people [ 6 ]. The disease pandemic and mortality showed the necessity for accurate and convenient approaches to diagnose, treat, and therapeutically monitor respiratory viral infections [ 7 , 8 ]. Several efforts have combined to rapidly develop a treatment and/or a vaccine to overcome the COVID-19 [ 9 ].…”
Section: Introductionmentioning
confidence: 99%
“…The copyright holder for this preprint this version posted December 8, 2020. ; https://doi.org/10.1101/2020.12.06.20244905 doi: medRxiv preprint primers and probe sets for virus detection has been evaluated, but there are still few studies that assess the sensitivity and specificity in the critical range of detection of the RT-PCR technique (Mathuria et al 2020). Among the most sensitive primer and probe sets are those for target N available by the US CDC (Vogels et al 2020, Etievant et al 2020 , .…”
Section: Discussionmentioning
confidence: 99%
“…Controversially, the molecular test of the same trademark was reported as highly accurate in the USA [9]. More information about PoC assays accuracy for Detection SARS-CoV-2 become available, and none of the published studies considers the non-ELISA PoC ones as adapted for detection of suspected patients either symptomatic or asymptomatic, due to the high risk of false negatives especially during the beginning days from the onset [10][11][12][13][14][15][16]. While some countries, specified and updated a pre-defined list of the approved Serological COVID-19 tests, based on the evaluation of their accuracy [6].…”
Section: Point Of Care (Poc) Serology Tests and Vaccination As Prmentioning
confidence: 99%