Lability of blocking antibody during ragweed pollen immunotherapy (RWI)

Local specific immunotherapy in allergic conjunctivitis

“…After diagnosis, the specific therapy is initiated (Smolin & O'Connor 1981;Del Prete et al 1989). Because local specific immunotherapy (LSI) has been used with success in extreme cases of allergic rhinitis (Nickelsen et al 1981;Wagner et al 1983), we evaluated the efficacy of LSI (Del Prete et al 1992) in the treatment of allergic conjunctivitis. However, while this therapy relieves symptoms, it does not exert a specific effect on the allergic reaction of the conjunctiva.…”

“…In fact, management of the inflammation is drug-and dose-dependent, with the consequent adverse effects connected with the prolonged use of steroids. Because local specific immunotherapy (LSI) has been used with success in extreme cases of allergic rhinitis (Nickelsen et al 1981;Wagner et al 1983), we evaluated the efficacy of LSI (Del Prete et al 1992) in the treatment of allergic conjunctivitis.…”