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Adhesive properties: a critical issue in transdermal patch development

“…The influence of the backing layer characteristics is less pronounced in a 90 peel adhesion test with respect to a 180 peel test, since a lower energy is required to deform the backing layer. Moreover, tests carried out at two peeling angles provide different information, since the 180 peel is a combination of tensile and shear processes, while the 90 peel depends only on tensile events; therefore, the standard deviations of data obtained by measuring the peel force at 90 is lower than that at 180 [21]. It is also to be noted that while both the 90 and 180 peel tests are being pulled at the same rate, the peel front of the 90 test is moving at twice the rate of 180…”

Tack properties of pressure‐sensitive adhesives

“…Finally, the adhesive properties of PSA have been checked by mechanical testing. The peel strength 5 increases generally with the thickness of the adhesive layer, up to a plateau. A commonly given explanation of this behavior is based on the viscoelastic dissipation of energy in the bulk of the adhesive joint.…”

Effects of miscibility on peel strength of natural-rubber-based pressure-sensitive adhesives

“…Especially, natural-rubber (NR)-based PSAs have been widely used, and they have a very long history. Recently, acrylic polymers and some kinds of block copolymers come to be used more and more, 3 but NR is still used in the greatest deal of all of the PSAs in Japan and cannot be completely replaced by acrylic polymers.…”