Label-free electrochemical DNA biosensor for rapid detection of mutidrug resistance gene based on Au nanoparticles/toluidine blue–graphene oxide nanocomposites

Peng, Hua-Ping; Hu, Yan; Liu, Pan; Deng, Ya-Ni; Wang, Peng; Chen, Wei; Liu, Ailin; Chen, Yuanzhong; Lin, Xinhua

doi:10.1016/j.snb.2014.10.059

Cited by 145 publications

(36 citation statements)

References 50 publications

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“…The differential pulse voltammogram showed a decrease in its peak current when the MDR gene hybridized with the immobilized capture probe. This showed an LOD of 2.95 pM in 60 minutes . The detection limit can be further lowered by using a redox intercalating dye such as methylene blue.…”

Section: Immobilized Electrochemical Dna Biosensorsmentioning

confidence: 99%

Rational Design of Electrochemical DNA Biosensors for Point‐of‐Care Applications

Maslova

Hsing

2017

ChemElectroChem

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Electrochemical DNA biosensors show great potential for the sensitive and sequence‐specific detection of disease pathogens. To date, although there are a large number of published articles showing various sensing strategies of an electrochemical biosensor, only a few of those studies actually reach the commercialization phase, because addressing one technical issue would usually be at the expense of another. Moreover, there are various adoptable formats in electrochemical biosensors. Current approaches may or may not use enzymes, immobilize DNA probes, label the sensing substrates with an electroactive reporter molecule, or any combination of these. Although much has been paid to individual advantages and disadvantages, there are a very limited number Review articles studying and analyzing the synergistic aspects of various detection strategies when combined with each other. It is the aim of this Review to highlight the hotspots for innovation when these strategies are used in tandem, in order to create more streamlined improvements in making a versatile biosensor platform that can be administered at point of care.

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Section: Immobilized Electrochemical Dna Biosensorsmentioning

confidence: 99%

Rational Design of Electrochemical DNA Biosensors for Point‐of‐Care Applications

Maslova

Hsing

2017

ChemElectroChem

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“…Authors in [18] developed a cholesterol sensor using NiO-Graphene nano composite film. Authors in [19] developed DNA FET sensor using AuNPs-Graphene composite films.…”

Section: Field-effect Transistor (Fet) Based Bio-sensormentioning

confidence: 99%

Bio-Sensing Applications of Graphene Based Composite Films

Maurya¹

2017

IJBSBE

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Graphene based composite materials have been extensively studied for the sensing applications attributing to their 2D structures, high conductivity, controlled modification and large specific surface areas, unique mechanical, optical, chemical, electrical, and catalytic properties. Therefore, a number of high quality sensors have been fabricated in recent years. Graphene based composite films (GCFs) that is base of such sensors can be prepared by combining Graphene with different functional nano-materials (carbon materials, noble metals, polymer materials, metal compounds etc.). In this review, we focus on the recent advances in bio-sensing applications of Graphene based composite films.

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“…Different authors employed a variety of nanomaterials such as graphene, 103,104 gold nanoparticles (AuNPs), 102,105 magnetic and nonmagnetic particles, 106,107 and carbon nanotubes 108 for modification of the base of the transducers.…”

Section: Nucleic Acid Electrochemical Biosensorsmentioning

confidence: 99%

Nanoscale virus biosensors: state of the art

Krejčová¹,

Michálek²,

Rodrigo³

et al. 2015

NDD

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Abstract:Since the beginning of the new millennium, viruses have shown huge epidemiological and pandemic potential: severe acute respiratory syndrome (SARS) in 2002, pandemic swine flu in 2009, and last but not least the West African Ebola outbreak in 2014. The occurrence and spread of the new virus in pandemic dimension poses a threat to the health and lives of 7 billion people worldwide. There is a growing urgency for highly sensitive and selective detection techniques, usable for a wide number of applications, including disease diagnosis, pharmaceutical research, agriculture, as well as preventive measures. Nanobiosensors represent a new promising tool for virus detection. This review gives a brief survey of the issue of viral detection, comprising diagnostics of target structure of viruses such as nucleic acids or proteins. This review covers different detection principles, methods of fabrication, and applications of virus biosensors.

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Label-free electrochemical DNA biosensor for rapid detection of mutidrug resistance gene based on Au nanoparticles/toluidine blue–graphene oxide nanocomposites

Cited by 145 publications

References 50 publications

Rational Design of Electrochemical DNA Biosensors for Point‐of‐Care Applications

Rational Design of Electrochemical DNA Biosensors for Point‐of‐Care Applications

Bio-Sensing Applications of Graphene Based Composite Films

Nanoscale virus biosensors: state of the art

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