Label free electrochemical aptasensor for ultrasensitive detection of ractopamine

Detection of Six β-Agonists by Three Multiresidue Immunosensors Based on an Anti-bovine Serum Albumin-Ractopamine-Clenbuterol-Salbutamol Antibody

“…From Table , Table S2, and Table , it can be seen that there is only one β-agonist (CL) with a detection limit of 0.1 ng·mL –1 in Table , four β-agonists (CL, SAL, RAC, and TUL) with a detection limit of 0.1 ng·mL –1 in Table S2, and six β-agonists (CL, SAL, RAC, TER, MAB, and TUL) with a detection limit of 0.1 ng·mL –1 in Table , which shows that the multiresidue detection performance of the GCE/GNP/RAC immunosensor is better than those of GCE/GNP/SAL and GCE/GNP/CL immunosensors. The three multiresidue immunosensors based on the anti-BSA-RAC-CL-SAL antibody manifest outstanding performance with a wide linear range and low detection limit, compared with the previous different material-modified electrodes for RAC detection, for example, Au/OMC/GCE (detection limit 1.49 ng·mL –1 ), 3D MnO 2 /RGO@nickel foam (detection limit 3.92 ng·mL –1 ), ATONPs/CNTs/GCE (detection limit 1.11 ng·mL –1 ), and MCF/CPE (detection limit 3.38 ng·mL –1 ), which can be ascribed to the high specific area of the GCE/GNP/β-agonist (RAC, CL, or SAL) caused by the nanoscale effect of the graphene, increasing the loading capacity of the β-agonists.…”

Recent trends in analysis of mycotoxins in food using carbon-based nanomaterials

“…They are usually selected from a combinatorial DNA library by systematic evolution of ligands exponential enrichment (SELEX) technology for binding to target analyte through folding into specific 3D-structures [ 34 , 53 ]. Aptamers possess a remarkable ability to interact with a wide range of molecular targets with high selectivity [ 54 ]. Unlike antibodies, aptamers are of low cost and easy to prepare with reproducible synthesis and exhibit high chemical and thermal stability with no significant toxicity [ 55 ].…”

Functionalized Carbon Nanotube-Decorated MXene Nanosheet-Enabled Microfluidic Electrochemical Aptasensor for Carcinoembryonic Antigen Determination

“…By contrast, an aptasensor has been considered as a desirable alternative for developing cancer biosensors. An aptasensor shows various advantages such as low cost, high affinity, obvious simplicity, and good chemical stability. − Especially, an electrochemical aptasensor has drawn considerable attention owing to its inherent advantages: (i) an electrochemical aptasensor shows high sensitivity and rapid response, which meets the requirement of rapid monitoring; − (ii) electrochemical response can be measured without using labels (i.e., label-free detection), and in this process, the operating cost is reduced through relatively simple operation steps; , and (iii) an electrochemical aptasensor can be effectively miniaturized and integrated with lab-on-chip equipment. Thus, the portability of the sensing platform can be greatly improved. − However, the sensing performance of electrochemical aptasensors relies heavily on the interface materials.…”