2023
DOI: 10.1021/acsinfecdis.3c00390
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Label-Free Citrate-Stabilized Silver Nanoparticles-Based, Highly Sensitive, Cost-Effective, and Rapid Visual Method for the Differential Detection of Mycobacterium tuberculosis and Mycobacterium bovis

Naresh Patnaik,
Ruchi Jain Dey

Abstract: Tuberculosis poses a global health challenge, and it demands improved diagnostics and therapies. Distinguishing between Mycobacterium tuberculosis (M. tb) and Mycobacterium bovis (M. bovis) infections holds critical "One Health" significance due to the zoonotic nature of these infections and inherent resistance of M. bovis to pyrazinamide, a key part of the directly observed treatment, shortcourse (DOTS) regimen. Furthermore, most of the currently used molecular detection methods fail to distinguish between th… Show more

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