Label and label-free based surface-enhanced Raman scattering for pathogen bacteria detection: A review

Liu, Yu; Zhou, Haibo; Hu, Ziwei; Yu, Guangxia; Yang, Danting; Zhao, Jinshun

doi:10.1016/j.bios.2017.02.032

Cited by 317 publications

(168 citation statements)

References 138 publications

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“…However, the spectrum of the strain 82/04 has changed a lot – we can see increased bands intensities at ~1221 cm, 1453, and 1583 cm -1 . The band at 1221 cm -1 is associated with proteins in cell membrane and also with cytosolic proteins [48]. The band at 1453 cm -1 also originates from protein bands (umbrella mode of methoxyl [4] and C-H bending mode of structural proteins [49]).…”

Section: Resultsmentioning

confidence: 99%

Strain-level typing and identification of bacteria – a novel approach for SERS active plasmonic nanostructures

et al. 2018

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One of the potential applications of surface-enhanced Raman spectroscopy (SERS) is the detection of biological compounds and microorganisms. Here we demonstrate that SERS coupled with principal component analysis (PCA) serves as a perfect method for determining the taxonomic affiliation of bacteria at the strain level. We demonstrate for the first time that it is possible to distinguish different genoserogroups within a single species, Listeria monocytogenes, which is one of the most virulent foodborne pathogens and in some cases contact with which may be fatal. We also postulate that it is possible to detect additional proteins in the L. monocytogenes cell envelope, which provide resistance to benzalkonium chloride and cadmium. A better understanding of this infectious agent could help in selecting the appropriate pharmaceutical product for enhanced treatment. Graphical abstractᅟ Electronic supplementary materialThe online version of this article (10.1007/s00216-018-1153-0) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

Strain-level typing and identification of bacteria – a novel approach for SERS active plasmonic nanostructures

et al. 2018

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“…Since Holt and Cotton first reported the SERS spectrum of bacteria, the identification and detection of microorganism by SERS have attracted high interest recently due to the spectroscopic fingerprint and nondestructive data acquisition in aqueous environment [74]. To date, there have been many SERS biosensors developed, especially based on a "magnetic separation" approach, which focus on bacterial pathogen detection.…”

Section: Optical Strategiesmentioning

confidence: 99%

Current and Emerging Technologies for Rapid Detection of Pathogens

Zeng¹,

Wang²,

Hu³

2018

Biosensing Technologies for the Detection of Pathogens - A Prospective Way for Rapid Analysis

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Foodborne diseases, caused by pathogenic bacteria, have become an important social issue in the field of food safety. It presents a widespread and growing threat to human health in both developed and developing countries. As such, techniques for the detection of foodborne pathogens and waterborne pathogens are urgently needed to prevent the occurrence of human foodborne infections. Although traditional culture-based bacterial isolation and identification are the "gold standard" methods with high preciseness, their drawbacks in time-consuming are inadequate for rapid detection of pathogen to reduce foodborne disease occurrence. Fortunately, with the development of biotechnologies and nanotechnologies, various kinds of new technologies for rapid detection of pathogens have been developed so far, such as nucleic acid-based methods, antibody-based methods, and aptamer-based assays. In this chapter, we summarized the principles and the application of some recent rapid detection technologies for pathogenic bacteria. Moreover, the advantages and disadvantages of the established and emerging rapid detection methods are addressed here.

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“…[ 14 ] SERS utilizes plasmonic resonance from metal nanostructures to enhance and detect vibrational Raman signals which hold detailed chemical information and serve as characteristic fingerprints of a specific analyte. [ 15 ] In order to establish multiplex detection using SERS, recent studies largely focused on endowing plasmonic nanostructures with selectivity by using aptamer‐ [ 16 ] or antibody‐conjugated [ 17 ] metal nanoparticles labeled with Raman reporter molecules for maximal SERS enhancement. [ 18 ] DNA aptamers and antibodies strongly bind to target analytes and enable selective detection from complex mixed samples.…”

Section: Introductionmentioning

confidence: 99%

Selective, Quantitative, and Multiplexed Surface‐Enhanced Raman Spectroscopy Using Aptamer‐Functionalized Monolithic Plasmonic Nanogrids Derived from Cross‐Point Nano‐Welding

Kyung

Baek

Han

et al. 2020

Adv Funct Materials

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Recent advances in surface-enhanced Raman spectroscopy (SERS) have resulted in multiplexing with unprecedented levels of sensitivity and selectivity in trace-amount detection. However, quantification of multiple trace-amount molecules with ng-level accuracy has yet to be demonstrated due to nonuniform distribution of SERS enhancement and random adsorption of molecules at low concentrations. While Raman reporter-free SERS is favorable for quantification in that the unique fingerprint spectra of molecules enable specific molecular identification, it has yet to be demonstrated due to poor reproducibility and insufficient SERS enhancement. Raman reporter-free multiplex SERS with highly accurate quantification is successfully realized by versatile aptamer-functionalized plasmonic Au nanogrids with uniform SERS enhancement. By cross-point nano-welding, monolithic Au nanogrids with excellent uniformity and high stability in aqueous media are produced. Raman reporter-free multiplex detection and highly accurate quantification of concentration and composition is realized at picomolar levels. As a demonstration, Au nanogrids functionalized with bisphenol A-specific aptamers successfully detect and quantify trace-amounts of bisphenol A (8.49 ng) from thermal receipt paper. Moreover, principal component analysis is applied to multiplex SERS spectra to establish a ternary composition map, which can potentially serve as a practical reference for future Raman reporterfree SERS.

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Label and label-free based surface-enhanced Raman scattering for pathogen bacteria detection: A review

Cited by 317 publications

References 138 publications

Strain-level typing and identification of bacteria – a novel approach for SERS active plasmonic nanostructures

Strain-level typing and identification of bacteria – a novel approach for SERS active plasmonic nanostructures

Current and Emerging Technologies for Rapid Detection of Pathogens

Selective, Quantitative, and Multiplexed Surface‐Enhanced Raman Spectroscopy Using Aptamer‐Functionalized Monolithic Plasmonic Nanogrids Derived from Cross‐Point Nano‐Welding

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