Lab on a smartphone (LOS): A smartphone-integrated, plasmonic-enhanced optoelectrowetting (OEW) platform for on-chip water quality monitoring through LAMP assays

Thio, Si Kuan; Bae, Sung Woo; Park, Sung-Yong

doi:10.1016/j.snb.2022.131543

Cited by 22 publications

(10 citation statements)

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“…SG combined with SNV achieved an accuracy of 98.7% for the training set and over 98.5% for the test set in CNN model. A low-cost lab-on-a-smartphone (LOS) for on-site monitoring of E. coli in environmental water, which was comprised of plasmonic-enhanced optoelectrowetting (OEW) device (Thio et al, 2022). Quintela et al 10.3389/fmicb.2022.1054782 Frontiers in Microbiology 19 frontiersin.org…”

Section: Emerging Biosensing Technologies and Approachesmentioning

confidence: 99%

Advances, applications, and limitations of portable and rapid detection technologies for routinely encountered foodborne pathogens

et al. 2022

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Traditional foodborne pathogen detection methods are highly dependent on pre-treatment of samples and selective microbiological plating to reliably screen target microorganisms. Inherent limitations of conventional methods include longer turnaround time and high costs, use of bulky equipment, and the need for trained staff in centralized laboratory settings. Researchers have developed stable, reliable, sensitive, and selective, rapid foodborne pathogens detection assays to work around these limitations. Recent advances in rapid diagnostic technologies have shifted to on-site testing, which offers flexibility and ease-of-use, a significant improvement from traditional methods’ rigid and cumbersome steps. This comprehensive review aims to thoroughly discuss the recent advances, applications, and limitations of portable and rapid biosensors for routinely encountered foodborne pathogens. It discusses the major differences between biosensing systems based on the molecular interactions of target analytes and biorecognition agents. Though detection limits and costs still need further improvement, reviewed technologies have high potential to assist the food industry in the on-site detection of biological hazards such as foodborne pathogens and toxins to maintain safe and healthy foods. Finally, this review offers targeted recommendations for future development and commercialization of diagnostic technologies specifically for emerging and re-emerging foodborne pathogens.

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Section: Emerging Biosensing Technologies and Approachesmentioning

confidence: 99%

Advances, applications, and limitations of portable and rapid detection technologies for routinely encountered foodborne pathogens

et al. 2022

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Section: Further Developments In Oewmentioning

confidence: 99%

“…With this interesting characteristic, later SCOEW studies have demonstrated the use of a smartphone as a low-intensity light source and the use of a polymer-based low-quality photoconductive material to offer cost-effective, portable, lab-on-a-chip (LOC) platforms. 50,55,56 Fig. 8 3D numerical simulation results showing electric field distribution and voltage profiles under various dark pattern illumination.…”

Section: Single-sided Continuous Optoelectrowetting (Scoew)mentioning

confidence: 99%

“…In recent years, Thio et al developed another smartphone-integrated SCOEW platform, called a lab-on-asmartphone (LOS), as a portable, low-cost, and fully integrated system that enables rapid, in situ monitoring of fecal indicator bacteria (FIB) and their associated pathogens in environmental water without the need for sophisticated laboratory equipment or skilled personnel. 55 The LOS was developed as a portable platform where three main components, a plasmonic-enhanced OEW device, a transparent heater, and a commercially available smartphone, are compactly integrated to eliminate the need for auxiliary optical and mechanical components (e.g., pumps and tubes to feed individual reagents, microscope and CCD camera for microscopy analyses) typically required for a conventional lab-on-a-chip (LOC) setup. As shown in Fig.…”

Section: A Smartphone-based Fluorescence Microscope For Realtime and ...mentioning

confidence: 99%

“…Using commercially available spatial light modulators such as liquid crystal displays (LCDs), digital micromirror devices (DMDs), and smartphones, millions of optical pixels are readily generated to modulate virtual electrodes in parallel on low-cost devices. A variety of applications have been involved with the OEW technology, such as droplet dispensing and merging, 51,52 integrated biosensing devices, 53,54 smartphone-based detection of water quality, 55,56 and biochemical and cell analyses. 57,58 This review paper highlights the technological advances of OEW and its applications as smartphone-integrated biosensors.…”

Section: Introductionmentioning

confidence: 99%

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A review of optoelectrowetting (OEW): from fundamentals to lab-on-a-smartphone (LOS) applications to environmental sensors

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Light‐Responsive Materials in Droplet Manipulation for Biochemical Applications

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et al. 2024

Advanced Materials

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Miniaturized droplets, characterized by well‐controlled microenvironments and capability for parallel processing, have significantly advanced the studies on enzymatic evolution, molecular diagnostics, and single‐cell analysis. However, manipulation of small‐sized droplets, including moving, merging, and trapping of the targeted droplets for complex biochemical assays and subsequent analysis, is not trivial and remains technically demanding. Among various techniques, light‐driven methods stand out as a promising candidate for droplet manipulation in a facile and flexible manner, given the features of contactless interaction, high spatiotemporal resolution, and biocompatibility. This review therefore compiles an in‐depth discussion of the governing mechanisms underpinning light‐driven droplet manipulation. Besides, light‐responsive materials, representing the core of light‐matter interaction and the key character converting light into different forms of energy, are particularly assessed in this review. Recent advancements in light‐responsive materials and the most notable applications are comprehensively archived and evaluated. Continuous innovations and rational engineering of light‐responsive materials are expected to propel the development of light‐driven droplet manipulation, equip droplets with enhanced functionality, and broaden the applications of droplets for biochemical studies and routine biochemical investigations.This article is protected by copyright. All rights reserved

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Lab on a smartphone (LOS): A smartphone-integrated, plasmonic-enhanced optoelectrowetting (OEW) platform for on-chip water quality monitoring through LAMP assays

Cited by 22 publications

References 50 publications

Advances, applications, and limitations of portable and rapid detection technologies for routinely encountered foodborne pathogens

Advances, applications, and limitations of portable and rapid detection technologies for routinely encountered foodborne pathogens

A review of optoelectrowetting (OEW): from fundamentals to lab-on-a-smartphone (LOS) applications to environmental sensors

Light‐Responsive Materials in Droplet Manipulation for Biochemical Applications

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