Lab-on-a-Chip: Frontier Science in the Classroom

Wietsma, Jan Jaap; Veen, Jan van der; Buesink, Wilfred; Berg, Albert van den; Odijk, Mathieu

doi:10.1021/acs.jchemed.7b00506

Cited by 32 publications

(37 citation statements)

References 25 publications

(39 reference statements)

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“…There are a number of topics that can be covered when teaching students about microfluidics; laboratory activities that focus on specific microfluidics concepts 19,20 as well as modules and whole courses on microfluidics 13,21,22 have been reported. The physics of fluids at the microscale is central to microfluidics.…”

Section: Formal Teaching About Microfluidicsmentioning

confidence: 99%

“Learning on a chip:” Microfluidics for formal and informal science education

2019

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Microfluidics is a technique for the handling of small volumes of liquids on the order of picoliters to nanoliters and has impact for miniaturized biomedical science and fundamental research. Because of its multi-and interdisciplinary nature (i.e., combining the fields of biology, chemistry, physics, and engineering), microfluidics offers much potential for educational applications, both at the university level as well as primary and secondary education. Microfluidics is also an ideal "tool" to enthuse and educate members of the general public about the interdisciplinary aspects of modern sciences, including concepts of science, technology, engineering, and mathematics subjects such as (bio)engineering, chemistry, and biomedical sciences. Here, we provide an overview of approaches that have been taken to make microfluidics accessible for formal and informal learning. We also point out future avenues and desired developments. At the extreme ends, we can distinguish between projects that teach how to build microfluidic devices vs projects that make various microscopic phenomena (e.g., low Reynolds number hydrodynamics, microbiology) accessible to learners and the general public. Microfluidics also enables educators to make experiments low-cost and scalable, and thereby widely accessible. Our goal for this review is to assist academic researchers working in the field of microfluidics and lab-on-a-chip technologies as well as educators with translating research from the laboratory into the lecture hall, teaching laboratory, or public sphere.

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Section: Formal Teaching About Microfluidicsmentioning

confidence: 99%

“Learning on a chip:” Microfluidics for formal and informal science education

2019

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“…It is hence crucial to be able to introduce the most basic concepts and capabilities of microfluidics at the high school or undergraduate level. Performing microfluidic experiments, however, necessitate the usage of microsystems, injection control instruments and microscopes [4][5][6][7][8][9] that are rarely available in undergraduate teaching laboratories.…”

Section: Capsum Company)mentioning

confidence: 99%

“…We have built in this document a digital millifluidic experimental setup allowing the kinetics quantification of the redox reaction of a dye, erythrosine B, with bleach. As compared to existing protocols aiming at introducing microfluidics concepts and available in the teaching literature [4][5][6][7][8][9] , the full setup can be built from materials and chemicals widely available in chemistry laboratories for undergraduate students. The setup does not require the acquisition of specific and more expensive instruments such as pressure regulators or microfabricated devices.…”

Section: Pedagogical Considerationsmentioning

confidence: 99%

An introduction to digital microfluidic concepts in chemistry using a macroscopic droplet generator

C¹,

Fattaccioli²,

Jacq³

2018

Preprint

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<div><div><div><div><div><div><p>This activity introduces digital microfluidics and the usage of aqueous droplets as independent chemical microreactors for reaction kinetics studies. Students build their own droplet generator from common macroscopic glassware and connecting parts, to create trains of millimetric droplets in which a redox reaction takes place. The activity allows working on reaction kinetics, hydrodynamics at low Reynolds number and image analysis at a macroscopic scale.</p></div></div></div></div></div></div>

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“…The interaction between proteins is studied by enzyme-linked immunosorbent assay (ELISA) (Johnson et al, 2017). In recent years, the Lab-on-a-Chip type of fluidic device has been introduced for chemical education (Tabassum et al, 2018;Wietsma et al, 2018) and used for organic and inorganic syntheses (Feng et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Development of Small-Scale Experiments for the Education of Chemical Engineering and Its Practice for Undergraduates

Kono¹,

Ichinohe²,

Konno³

et al. 2019

Preprint

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A series of small-scale/micro-scale experiments used for the education of undergraduate students in chemical engineering courses have been developed. Based on the “small-scale/micro-scale” concept, the experiments were developed to provide an intuitive understanding of chemical processes, both by increasing the visibility of these chemical processes and by making the apparatus compact (desktop size). Nine experiments were developed that are relevant to the fields of thermal engineering, fluid engineering, unit operations, and reaction engineering. These experiments were introduced during the educational experiment course for undergraduates in the chemical engineering program.

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Lab-on-a-Chip: Frontier Science in the Classroom

Cited by 32 publications

References 25 publications

“Learning on a chip:” Microfluidics for formal and informal science education

“Learning on a chip:” Microfluidics for formal and informal science education

An introduction to digital microfluidic concepts in chemistry using a macroscopic droplet generator

Development of Small-Scale Experiments for the Education of Chemical Engineering and Its Practice for Undergraduates

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