La schizophrénie tardive est-elle secondaire à des processus neurodégénératifs? Une revue de la littérature

Lagodka, Aurélie; Robert, P.

doi:10.1016/j.encep.2008.06.008

Cited by 24 publications

(16 citation statements)

References 35 publications

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“…Only the third of the EOS with CT-scans (2/6) presented abnormal results at current evaluation. These findings suggest the development of greater cerebrovascular vulnerability in VLOSLP than in EOS, thus corroborating neurodegenerative/neurovascular reports of previous studies [7,26,36,38].…”

Section: Discussionsupporting

confidence: 80%

“…The International Late-Onset Schizophrenia Group proposed that early-onset schizophrenia or EOS (onset before the age of 40) and LOS (onset after 40 years old) would be more similar than different in terms of symptoms [5,6] whereas VLOSLP (onset after 60 years old) would present with a lower prevalence of formal thought disorder and affective blunting, and a higher prevalence of visual hallucinations than EOS [5]. This nomenclature may have had face validity and clinical utility, but required further investigation in several domains, especially regarding the differential clinical symptomatology with EOS [5,7].…”

Section: Introductionmentioning

confidence: 99%

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Elderly patients with very late-onset schizophrenia-like psychosis and early-onset schizophrenia: Cross-sectional and retrospective clinical findings

Girard¹,

Simard²

2012

OJPsych

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Section: Discussionsupporting

confidence: 80%

Section: Introductionmentioning

confidence: 99%

Elderly patients with very late-onset schizophrenia-like psychosis and early-onset schizophrenia: Cross-sectional and retrospective clinical findings

Girard¹,

Simard²

2012

OJPsych

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“…Some researchers believe that patients with late‐onset schizophrenia are prone to have cognitive deficits and microscopic abnormalities . Late onset schizophrenia cases may include neurodegenerative diseases that are detected only by neuropathological examination or continuous neuroimaging follow‐up …”

Section: Discussionmentioning

confidence: 99%

“…[23][24][25] Late onset schizophrenia cases may include neurodegenerative diseases that are detected only by neuropathological examination or continuous neuroimaging follow-up. [26][27][28] The aetiology of schizophrenia is unknown, and there is no biological marker for it. In this sense, schizophrenia is a syndrome, and the late-onset cases are no exception.…”

Section: Discussionmentioning

confidence: 99%

Clinical features of late‐onset schizophrenia in Japan: comparison with early‐onset cases

et al. 2013

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Background: Although the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders abandoned the use of the specifier 'late-onset', a considerable number of studies have reported clinical characteristics of late-onset schizophrenia. Still, only limited research has been conducted on late-onset schizophrenia, especially in Asian countries. In this epidemiological study, the clinical characteristics of late-onset schizophrenia were examined in comparison with early-onset schizophrenia. Methods: All patients with schizophrenia admitted to the psychiatric ward of Jichi Medical University Hospital between 1 April 1993 and 31 March 2006 were divided into two groups according to age at first onset: ≥40 years (late-onset group) and <40 years (early-onset group). The sex ratio, presence or absence of depression, schizophrenia subtype, premorbid character, marital history, and employment history at first onset were compared between the two groups. Results: Of the 316 patients with schizophrenia identified, 38 patients were assigned to the late-onset group and 278 patients to the early-onset group. Mean age at onset was 23.9 1 8.2 years for all men and 28.0 1 13.5 years for all women. The late-onset group was characterized by more women, more paranoid type, more depressive symptoms, less introverted premorbid character, better premorbid adaptation and less neuroleptics. Conclusion: The characteristics of late-onset schizophrenia in Japan are in line those reported previously.

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“…Récemment, une entité clinique nouvelle, caractéri sée par une tauopathie limbique, a été décrite dont les manifestations psychotiques pourraient se déve lopper spontanément à l'âge avancé où être déclen chées par une pathologie cérébrovasculaire [30]. [46,47].…”

Section: Aspects éTiopathogéniques De La Schizophrénie Tardiveunclassified

Schizophrénies et troubles délirants tardifs à l'âge avancé

2015

Swiss Arch Neurol Psychiatr

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La schizophrénie tardive est-elle secondaire à des processus neurodégénératifs? Une revue de la littérature

Cited by 24 publications

References 35 publications

Elderly patients with very late-onset schizophrenia-like psychosis and early-onset schizophrenia: Cross-sectional and retrospective clinical findings

Elderly patients with very late-onset schizophrenia-like psychosis and early-onset schizophrenia: Cross-sectional and retrospective clinical findings

Clinical features of late‐onset schizophrenia in Japan: comparison with early‐onset cases

Schizophrénies et troubles délirants tardifs à l'âge avancé

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