La implementación de la profilaxis preexposición podría evitar la mayoría de las nuevas infecciones por el VIH en hombres que tienen sexo con hombres y mujeres transexuales

Ayerdi, Oskar; Vera, Mar; Núñez, Julián; Lopez, Travis; Garcia, C. Escalante; Utrilla, Montserrat Raposo; Pérez, Vicente Estrada; Guerrero, Jorge Del Romero; Martín, C. Rodríguez

doi:10.1016/j.rce.2019.02.001

Cited by 9 publications

(3 citation statements)

References 10 publications

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“…These data confirm that HIV infection continues to be a highly prevalent public health concern, especially in the MSM population [5]. Although new strategies such as pre-exposure prophylaxis (PReP) have emerged [6,7], prevention through condoms remains the most recommended method due to its accessibility and effectiveness [8,9]. However, the lack of condom use as a prophylactic method against HIV has contributed to an increase in the transmission of HIV and other sexually transmitted diseases (STDs), such as syphilis, gonorrhea, hepatitis, urethritis, genital warts and chlamydia in this population [10].…”

Section: Introductionmentioning

confidence: 64%

Chemsex Practices and Health-Related Quality of Life in Spanish Men with HIV Who Have Sex with Men

Ruiz‐Robledillo

Portilla-Tamarit

Alcocer-Bruno

et al. 2021

JCM

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Chemsex, a new risky sexual behavior involving participation in sexual relations under the influence of drugs, has shown a significantly increased prevalence in recent years. This fact entails a serious public health issue, especially when Chemsex is practiced by individuals with an HIV (Human Immunodeficiency Virus) diagnosis. Hence, analyzing the characteristics of Chemsex practices, associated sexual practices and the health outcomes of individuals who participate in Chemsex, is extremely important. The main aim of the present study is to analyze the prevalence and characteristics of the practice of Chemsex in a sample of 101 men with HIV who have sex with men who attended the Department of Infectious Diseases of the General University Hospital of Alicante (Spain). Furthermore, the association between Chemsex and Health-Related Quality of Life (HRQoL) was also assessed. Chemsex and sexual practices were evaluated by employing a questionnaire applied on an ad hoc basis. HRQoL was assessed by employing the Medical Outcomes Study HIV Health Survey (MOS-HIV). In total, 40.6% of the participants had practiced Chemsex during the last year. When sexual practices were compared between those individuals who practiced Chemsex and those who did not, the former presented a higher level of risky sexual behaviors, especially with occasional and multiple sexual partners. Regarding HRQoL, those individuals who practiced Chemsex exhibited a poorer HRQoL in the majority of domains, especially those participants who practiced it with a higher intensity. The present study points out the high prevalence of Chemsex practice between men with HIV who have sex with men in Spain. Moreover, this study highlights the negative effects of Chemsex on HRQoL, probably due to the mixed effects of higher levels of risky sexual practices and the consequences of drug consumption.

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Section: Introductionmentioning

confidence: 64%

Chemsex Practices and Health-Related Quality of Life in Spanish Men with HIV Who Have Sex with Men

Ruiz‐Robledillo

Portilla-Tamarit

Alcocer-Bruno

et al. 2021

JCM

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“…A study conducted in Madrid, Spain among MSM and transgender women (97.8% were cisgender men) recently diagnosed as having HIV, found that 86.6% had an indication for PrEP according to the national AIDS study group guidelines, a sensitivity similar to the one showed by the best operating guidelines [29]. Yet, our ability to make comparisons with previous studies is limited because most studies evaluated guidelines' ability to identify HIV seroconversion in the US using the US CDC guidelines.…”

Section: Discussionmentioning

confidence: 94%

Different guidelines for pre-exposure prophylaxis (PrEP) eligibility estimate HIV risk differently: an incidence study in a cohort of HIV-negative men who have sex with men, Portugal, 2014–2018

Meireles

Plankey

Rocha³

et al. 2020

Eurosurveillance

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We aimed to measure the association between guideline-specific eligibility and HIV seroconversion. Methods: We studied 1,254 participants from the Lisbon Cohort of men who have sex with men with at least two evaluations between March 2014 and March 2018, corresponding to 1,724.54 person-years (PY) of follow-up. We calculated incidence rates (IR) according to each guideline eligibility definition and incident rate ratios (IRR) to test the association between eligibility at baseline and HIV seroconversion. Results: We found 28 incident cases (IR: 1.62/100 PY; 95% confidence interval (CI) 1.12-2.35). Guidelines' sensitivity varied from 60.7% (EACS) to 85.7% (PNHS) and specificity varied from 31.8% (US CDC) to 51.5% (EACS). IR was highest among those defined as eligible by the PNHS guideline (2.46/100 PY; IRR = 4.61; 95% CI: 1.60-13.27) and lowest for the WHO guideline (1.89/100 PY; IRR = 1.52; 95% CI: 0.69-3.35). Conclusions: Being identified as eligible for PrEP was associated with a higher risk of infection. The magnitude of risk varied according to the guideline used. However, the number of HIV infections identified among ineligible participants highlights the potential for missing people who need PrEP.

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“…Los diferentes tipos de TAR autorizados por parte del FDA, se pueden agrupar en 5 grandes familias (U.S. Department of Health and Human Services, 2019a El Plan Nacional Sobre el SIDA y Grupo de Expertos PrEP (2018) recomiendan la implementación de la PrEP en el territorio Español, pero en la actualidad la implementación de la PrEP en España se encuentra parada en la fijación de precios, por actuaciones administrativas sin aparente fecha de fin y por no ocupar un puesto elevado en la agenda de los partidos políticos españoles (García et al, 2018), a pesar de que nuevas investigaciones destacan que la administración de PrEP podría evitar la mayoría de las nuevas infecciones entre HSH y mujeres transexuales en España (Aguirrebengoa et al, 2019).…”

Section: Vías De Transmisión Del Vih Y Factores De Riesgounclassified

El papel de las funciones ejecutivas en la calidad de vida en personas con VIH en situación de vulnerabilidad social

Marijuán¹

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La implementación de la profilaxis preexposición podría evitar la mayoría de las nuevas infecciones por el VIH en hombres que tienen sexo con hombres y mujeres transexuales

Cited by 9 publications

References 10 publications

Chemsex Practices and Health-Related Quality of Life in Spanish Men with HIV Who Have Sex with Men

Chemsex Practices and Health-Related Quality of Life in Spanish Men with HIV Who Have Sex with Men

Different guidelines for pre-exposure prophylaxis (PrEP) eligibility estimate HIV risk differently: an incidence study in a cohort of HIV-negative men who have sex with men, Portugal, 2014–2018

El papel de las funciones ejecutivas en la calidad de vida en personas con VIH en situación de vulnerabilidad social

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