La glomérulonéphrite aiguë post-streptococcique de l’enfant dans le sud tunisien : étude rétrospective de 12 ans

Maalej, B.; Amor, M. Ben; Jallouli, Manel; Wèli, Manel; Charfi, Mohamed Ridha; Abdelkefi, Yassine; Chakroun-Walha, Olfa; Kamoun, Khaoula; Hachicha, J.; Rekik, Noureddine; Gargah, Tahar; Gargouri, L.; Mahfoudh, A.

doi:10.1016/j.nephro.2018.04.001

Cited by 3 publications

(3 citation statements)

References 12 publications

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“…Glomerular hematuria is almost a universal finding. Our study showed 31.1% with gross hematuria which is comparable to another study [13]. While dyspnea may be a presenting feature in around 5% of patients done in a study by Burke and Titus, there were no patients in our study with complaints of dyspnea [14].…”

Section: Discussionsupporting

confidence: 88%

“…The most common presenting feature in this age group was edema in 53 (68.8%) and gross hematuria in 24 (31.1%) patients, which was comparable to a study done by Maalej et al in which edema and hematuria were noted in 135 (75.8%) and 114 (64%) cases, respectively. Forty-two (54.5%) developed acute renal injury (creatinine based on age), whereas in a Tunisia study, 37% developed renal injury [13].…”

Section: Discussionmentioning

confidence: 89%

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Acute Post-streptococcal Glomerulonephritis in a Pediatric Population: A Five-Year Retrospective Study

Bajracharya,

Khadgi,

Shrestha

et al. 2024

Cureus

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Introduction: Post-streptococcal glomerulonephritis is a kidney disease that occurs after infection with a certain strain of streptococcal bacteria. It has a high hospitalization rate, especially in developing countries. It is characterized by the sudden appearance of edema, hematuria, proteinuria, and hypertension. The objective of this retrospective descriptive study conducted at James L. Gordon Memorial Hospital in Olongapo, Zambales, Philippines, is to analyze the demographic distribution, clinical presentation, complication, and outcome of acute post-streptococcal glomerulonephritis (APSGN) in a pediatric population.Methods: A retrospective descriptive study was done in patients (below 18 years of age) admitted with the diagnosis of post-streptococcal glomerulonephritis during a five-year period in the pediatric ward of a tertiary hospital in the Philippines. All patients underwent detailed clinical history and examination and were closely monitored during treatment. The course of disease progression was closely monitored and recorded.Results: Seventy-seven children were treated for APSGN with a mean age of 7.8 years and with standard deviation of 3.85. Edema and gross hematuria were noted in 53 (68.8%) and 24 (31.1%) cases, respectively. Hypertension was present in 54 patients (70.1%). Among those 54 patients, 49 (63.6%) patients developed acute renal injury (based on normal creatinine for age), three cases (3.8%) had pleural effusion, and two patients (2.5%) developed hypertensive encephalopathy. All patients underwent KUB (kidneys, ureters, and bladder) ultrasound, among which 13 (16.88%) had diffuse parenchymal swelling which improved and eventually were discharged. Increased blood urea nitrogen (BUN) was noted in 60-65% of patients. Hypoalbuminemia and lower hemoglobin were also quite common. There was no mortality during treatment and hospital stay.Conclusions: APSGN remains one of the most common causes of glomerulonephritis in the region. Edema, hypertension, and hematuria were the most common presenting features. Early identification and comprehensive monitoring and management are required to prevent morbidity and mortality. The prognosis is generally good if early treatment is done.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 89%

Acute Post-streptococcal Glomerulonephritis in a Pediatric Population: A Five-Year Retrospective Study

Bajracharya,

Khadgi,

Shrestha

et al. 2024

Cureus

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“…In tropical regions, skin infection accounts for at least 50% of acute post-streptococcal glomerulonephritis [30], which acts as a strong risk factor for developing chronic kidney disease in later life [31]. In contrast, it has been accepted for many years that acute rheumatic fever occurs only following GAS pharyngitis; however, this is unlikely to be the case in tropical settings [32].…”

Section: Complications Of Scabiesmentioning

confidence: 99%

A Review of Scabies: An Infestation More than Skin Deep

2018

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Human scabies, a common infestation, has a worldwide distribution with a variable impact and presentation depending on the clinical situation. In developed, high-income settings, health institution and residential home outbreaks challenge health and social care services. In resource-poor settings, it is the downstream sequelae of staphylococcal and streptococcal bacteraemia, induced by scratching, which have a significant impact on the long-term health of communities. Over the past decade scabies has been recognised as a “neglected tropical disease” (NTD) by the World Health Organisation, has an accepted practical system of global diagnostic criteria and is being adopted into integrated programmes of mass drug administration for NTDs in field settings. This review seeks to summarise the recent advances in the understanding of scabies and highlight the advocacy and research headlines with their implication for diagnosis and management of outbreaks and individuals. In addition, it will indicate the priorities and questions that remain.

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Clinical characteristics of acute glomerulonephritis with presentation of nephrotic syndrome at onset in children

Wang

Deng

et al. 2020

International Immunopharmacology

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La glomérulonéphrite aiguë post-streptococcique de l’enfant dans le sud tunisien : étude rétrospective de 12 ans

Cited by 3 publications

References 12 publications

Acute Post-streptococcal Glomerulonephritis in a Pediatric Population: A Five-Year Retrospective Study

Acute Post-streptococcal Glomerulonephritis in a Pediatric Population: A Five-Year Retrospective Study

A Review of Scabies: An Infestation More than Skin Deep

Clinical characteristics of acute glomerulonephritis with presentation of nephrotic syndrome at onset in children

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