La gigantomastie gravidique à l’Institut du Cancer de Dakar: à propos de 2 cas

Ka, Sidy; Thiam, Jaafar; Mané, Maïmouna; Somé, Rolland Ollo; Niang, Rokhaya; Goudiaby, Céline; Dem, Ahmadou

doi:10.11604/pamj.2015.22.314.8085

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2023

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“…Gestational gigantomastia is characterized by dense stromal fibrosis, dilatation of ducts, edema of the periductal regions and connective tissue, and hyperplasia of the stroma, ducts, lobules, and acini. 13 In nonpregnancy-related gigantomastia, infiltration of lymphocytes and plasma cells has been observed. 10 In this case report, infiltration of lymphocytes and plasmacytic cells was noticed.…”

Section: Discussionmentioning

confidence: 99%

Idiopathic gigantomastia exacerbated during pregnancy. Its relationship with autoimmunity: A case report

Biancha‐Vasco,

Muñoz P.,

Gómez

et al. 2023

Int J of Rheum Dis

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Gigantomastia is a rare entity characterized by diffuse and excessive breast enlargement. It mainly occurs during puberty and pregnancy as a consequence of hormonal fluctuations. We report an unusual case of gigantomastia in a 29‐year‐old woman with a history of personal and familiar autoimmune phenomena. She had autoimmune thyroiditis and several positive autoantibodies, and developed 3 crises of the disease, 1 related to pregnancy (possibly hormone‐mediated), and 2 unrelated to pregnancy in which an autoimmune role is raised based in clinical, histological and laboratory findings. Immunological aspects that may be involved in this presentation of the disease are discussed.

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Section: Discussionmentioning

confidence: 99%