La distribution de quatorze marqueurs génétiques dans la population de l'île de Corse (France)

Varesi, Laurent; Memmì, Marc; Moral, Pedro; Mameli, G. E.; Succa, Valeria; Vona, Giuseppe

doi:10.3406/bmsap.1996.2424

Cited by 11 publications

(13 citation statements)

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“…Finally, the study of mtDNA confirms what had already been shown from the analysis of Corsica's genetic structure by means of the classic markers (Vona et al, 1995;Moral et al, 1996;Varesi et al, 1996;Memmí et al, 1998). That is, the greater genetic affinity of the Corsicans to Sardinians compared to the other Mediterranean and European populations, including Tuscany, and a clear-cut differentiation from Africa, which has not been noted by other authors .…”

Section: Mtdna In Corsicanssupporting

confidence: 88%

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Mitochondrial control-region sequence variation in the Corsican population, France

et al. 2000

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The mtDNA sequence variation of the hypervariable segment I of the control region was studied in 47 unrelated individuals of Corsican origin from Corte (Corsica, France). Thirty‐one different sequences were identified by 40 variable sites, of which five involve transversions. The nucleotide diversity among the sequences was estimated as 1.03%. The pairwise difference agreed with the model proposed by Rogers and Harpending ([1992] Mol Biol Evol 9:552–569) and appeared bell‐shaped, with only one peak at 3.71, indicating the occurrence of a single episode of demographic expansion roughly 14,443 to 41,584 years ago. From our results it seems that the ancestral Corsican population expanded more recently than all other studied European populations. Compared to other populations by genetic distances and a neighbor‐joining tree, Corsicans appear most closely linked to the Basques and Sardinians than to other populations. Although the results substantiate an east‐to‐west migration, some problems are evident: 1) the estimates of demographic expansion are not in agreement with paleontological data; 2) the expansion occurred later than the expansion of the Sardinian population; and 3) the genetic affinity between Corsicans, Basques, and Sardinians. Answers will need to come from archaeological, paleontological, genetic, geological, and climatological observations. Finally, the study of mtDNA confirms what had already been shown with classic genetic markers. Am. J. Hum. Biol. 12:339–351, 2000. © 2000 Wiley‐Liss, Inc.

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Section: Mtdna In Corsicanssupporting

confidence: 88%

“…The expansion of the population in Corsica could have happened by way of a migration from Sardinia, in particular from the northern area called Gallura-a theory seemingly strengthened by the genetic affinity seen from the study of the classic markers (Vona et al, 1995;Moral et al, 1996;Varesi et al, 1996;Memmí et al, 1998).…”

Section: Discussionmentioning

confidence: 99%

Mitochondrial control-region sequence variation in the Corsican population, France

et al. 2000

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“…In this work, new data on the microregions of the South (Bonifacio), the Northwest (Balagna) and part of the data on the Northeast (Bastia) are presented, data which are to be added to previously published works (Memmì et al, 1998;Vona et al, 1995;Varesi et al, 1996).…”

Section: Discussionmentioning

confidence: 99%

“…Data concerning the micro-regions of Balagna (Northwest), Bonifacio (Extreme South), and in part Bastia (Northeast) are reported here for the first time. The data for Corte (Center) and Ajaccio (Southwest) are taken from works previously published by some of us (Memmì et al, 1998;Vona et al, 1995;Varesi et al, 1996).…”

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confidence: 99%

Genetic structure and affinities of the corsican population (France): Classical genetic markers analysis

Vona

Moral

Memmì

et al. 2003

American J Hum Biol

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The frequencies of 19 classical genetic markers for a total of 54 alleles were studied in a sample of 1,164 individuals born and residing in five different regions of Corsica. The results, which are also discussed in the context of the Mediterranean populations, show the existence within Corsica of a certain genetic differentiation between north and south which follows the linguistic subdivision differentiation. Compared to the other Mediterranean populations, Corsica also appears to be greatly differentiated from the populations of regions such as France and Tuscany, regions which have had great political and cultural influence. The Mediterranean population most comparable to Corsica is Sardinia. Despite their common origin, however, they do not prove to be absolutely identical. The genetic characteristics of Corsica and their relationship with the Mediterranean populations are interpreted in terms of demographic and matrimonial structure, isolation, and genetic drift.

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“…Similar megalithic monuments and turriform buildings are found during prehistoric times and they were occupied by the same people during the historical period, namely Phoenicians, Etruscans (in Corsica and Sardinia), Greeks, Carthaginians, Vandals, Byzantines, Pisans (in Corsica and Sardinia), Genovese (in Corsica and Sardinia) and Aragonese (especially in Balearics and Sardinia). Previous studies about the genetic variability of the Corsican population carried out with different kinds of genetic markers including HLA serological polymorphisms and class II molecular markers (18–25) have shown the singularity of Corsica among the French regions and a genetic proximity with Sardinia. The aim of the present work was to analyze the genetic structure of the islander populations with highly informative markers.…”

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confidence: 99%

West Mediterranean islands (Corsica, Balearic islands, Sardinia) and the Basque population: contribution of HLA class I molecular markers to their evolutionary history

et al. 2001

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The genetic structure of Balearic islands (Corsica and Sardinia), situated on the same trans-Mediterranean maritime routes and having very similar histories, were compared and their position among the neighbouring Caucasian populations was inferred. For this purpose, three HLA loci (HLA-A, -B and -Cw) were typed at the DNA level in these populations and the allelic and haplotypic frequencies were estimated. Because previous studies have shown common genetic features in the Sardinians and Basques, HLA-Cw molecular typing was also performed in a sample of French Basques in order to establish the haplotypic structure of this population for a more accurate comparison with the three others. By its allelic composition, the Corsican population has an intermediate position between the two other islander populations. Its close relationship with the Sardinian population, however, was clearly revealed by the phylogenetic analysis which also suggests a proximity with eastern Mediterranean peoples, whereas the Balearic islands are more narrowly related to Spain and western Europe. Peculiarities were observed in the distributions of some common haplotypes in the populations of the islands that confirm the results of the phylogenetic analysis and could be related to their history. Noteworthy is the presence of the HLA-A30-Cw*0501-B18 haplotype at frequencies approximately 2% in Corsica and the Balearic islands, yet the estimated frequencies of this haplotype are much lower than in the Sardinian and Basque populations.

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La distribution de quatorze marqueurs génétiques dans la population de l'île de Corse (France)

Cited by 11 publications

References 0 publications

Mitochondrial control-region sequence variation in the Corsican population, France

Mitochondrial control-region sequence variation in the Corsican population, France

Genetic structure and affinities of the corsican population (France): Classical genetic markers analysis

West Mediterranean islands (Corsica, Balearic islands, Sardinia) and the Basque population: contribution of HLA class I molecular markers to their evolutionary history

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