l-Tyrosine and l-tryptophan membrane transport in erythrocytes and antidepressant drug choice

Azorin, Jean‐Michel; Bovier, P.; Widmer, Jean; Jeanningros, Régine; Tissot, R

doi:10.1016/0006-3223(90)90587-r

Cited by 9 publications

(2 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus it is generally considered as a safe diet in nemaline myopathy 12 and in the treatment of maternal phenyloketonuria. 13 It is suggested as an antidepressant 14,15 and used as a great 'anti-stress' supplement. 16 Moreover, it is a precursor of human skin pigment -melanin, 17 and as a hormone-like regulator of melanocytes function.…”

Section: Introductionmentioning

confidence: 99%

Structural, spectroscopic, magnetic behavior and DFT investigations ofl-tyrosinato nickel(ii) coordination polymer

et al. 2015

View full text Add to dashboard Cite

New 1D-coordination polymer {[Ni(L-Tyr) 2 (m-4,4 0 -bpy)]Á4H 2 O} n (1) (L-Tyr = L-tyrosine, 4,4 0 -bpy = 4,4 0 -bipyridine) is composed of L-tyrosinate anions chelated nickel(II) centres via N amino and O carboxylate atoms, whereas the apices of the elongated octahedral coordination sphere are occupied by the N atoms of 4,4 0 -bipyridine. Its molecular structure was determined by single-crystal X-ray diffraction and characterized using vibrational (FT-IR), Raman spectroscopy (FT-Raman), electronic (NIR-Vis-UV) and high field electron paramagnetic resonance (HF-EPR) spectroscopy and thermal (TG-DTA, DSC) and magnetic methods. The tetragonality distortion parameter (T) equals 0.945. The g x , g y and g z parameters (HF-EPR spectra) are slightly temperature dependent and the set g x = 2.178(5), g y = 2.156(4), g z = 2.19(1), D = À5.76(2) cm À1 , E = À0.41(1) cm À1 was found at 5 K. The analysis of the temperature and field dependent magnetization shows the weakness of magnetic interactions in 1.

show abstract

Section: Introductionmentioning

confidence: 99%

Structural, spectroscopic, magnetic behavior and DFT investigations ofl-tyrosinato nickel(ii) coordination polymer

et al. 2015

View full text Add to dashboard Cite

show abstract

“…It helps in the function of organs responsible for making and regulating hormones, including the adrenal, thyroid, and pituitary glands. It is involved in the structure of almost every protein in the body (Azori et al, 1990;Bergès et al, 2011;Tumilty et al, 2011;Van Spronsen et al, 2001;Marquez and Dunford, 1995).…”

Section: Introductionmentioning

confidence: 99%

DFT and PM3 Computational Studies of the Reaction Mechanism of the Oxidation of L-Tyrosine by Iodine in the Gas Phase

Shallangwa

Uzairu

Ajibola

et al. 2014

Aceh Int. J. Sci. Technol

View full text Add to dashboard Cite

The oxidation of L-Tyrosine by molecular iodine was studied using semi-empirical and density functional theory methods. Molecular information such as net charges, values of frontier orbital energies, composition, proportions and bonding contribution were obtained and analyzed. Thus, possible reactive sites were proposed and the reaction mechanism was postulated. The postulated transition states, intermediates and products were also computed using the PM3 and DFT methods. Computed enthalpies of the oxidation reaction at standard conditions for the PM3 and DFT calculation were 216.97 kJ/mol and -36327404.72 kJ/mol respectively. The calculated ΔG o and ΔS o , for the transition states according to the DFT model were both large and negative indicating that the processes were exergonic associative substitution reactions.

show abstract

Transport of Amino Acids

Lefauconnier¹

1992

Physiology and Pharmacology of the Blood-Brain Barrier

View full text Add to dashboard Cite

l-Tyrosine and l-tryptophan membrane transport in erythrocytes and antidepressant drug choice

Cited by 9 publications

References 15 publications

Structural, spectroscopic, magnetic behavior and DFT investigations ofl-tyrosinato nickel(ii) coordination polymer

Structural, spectroscopic, magnetic behavior and DFT investigations ofl-tyrosinato nickel(ii) coordination polymer

DFT and PM3 Computational Studies of the Reaction Mechanism of the Oxidation of L-Tyrosine by Iodine in the Gas Phase

Transport of Amino Acids

Contact Info

Product

Resources

About