L’orientation spatiale chez le primate

Wirth, Sylvia; Baraduc, Pierre

doi:10.1051/medsci/20183401010

Cited by 4 publications

(1 citation statement)

References 13 publications

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“…This point is brought out by the high firing rate when the monkey looked towards the ball landmark when it is in place p1 ( Fig. 5F), but no or less firing when the monkey is in place p2 or p3 ( Fig 5G) (Wirth and Baraduc, 2018;Wirth et al, 2017). In addition, 17% of the total population responded when the animal was in one or more places in the virtual environment without significant modulation by where the animal was looking.…”

Section: Visually Supported Spatial Representations In Primates In a mentioning

confidence: 95%

Spatial representations in the primate hippocampus, and their functions in memory and navigation

Rolls

Wirth

2018

Progress in Neurobiology

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Hippocampal spatial view neurons in primates respond to the place where a monkey is looking, with some modulation by place. In contrast, hippocampal neurons in rodents respond mainly to the place where the animal is located. We relate this difference to the development of a fovea in primates, and the highly developed primate visual system which enables identification of what is at the fovea, and a system for moving the eyes to view different parts of the environment. We show that the spatial view representation in primates is allocentric, and provide new animations using recorded neuronal activity to illustrate this. We also show that this spatial representation becomes engaged in tasks in which the location 'out there' in a scene of objects and rewards must be remembered. We show that this representation of space being viewed provides a framework for the encoding of episodic memory and the recall of these memories in primates including humans, with hippocampal neurons responding for example in a one-trial object / place recall task. These functions of the primate hippocampus in scene-related memory, provide a way for the primate hippocampus to contribute to actions in space and navigation. We consider in a formal model the mechanisms by which these different spatial representations may be formed given the presence of the primate fovea, and how these mechanisms may contribute to the representations found during navigation in a virtual environment.

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Section: Visually Supported Spatial Representations In Primates In a mentioning

confidence: 95%

Spatial representations in the primate hippocampus, and their functions in memory and navigation

Rolls

Wirth

2018

Progress in Neurobiology

Self Cite

138

161

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Spatial coordinate transforms linking the allocentric hippocampal and egocentric parietal primate brain systems for memory, action in space, and navigation

Rolls

2019

Hippocampus

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A theory and model of spatial coordinate transforms in the dorsal visual system through the parietal cortex that enable an interface via posterior cingulate and related retrosplenial cortex to allocentric spatial representations in the primate hippocampus is described. First, a new approach to coordinate transform learning in the brain is proposed, in which the traditional gain modulation is complemented by temporal trace rule competitive network learning. It is shown in a computational model that the new approach works much more precisely than gain modulation alone, by enabling neurons to represent the different combinations of signal and gain modulator more accurately. This understanding may have application to many brain areas where coordinate transforms are learned. Second, a set of coordinate transforms is proposed for the dorsal visual system/parietal areas that enables a representation to be formed in allocentric spatial view coordinates. The input stimulus is merely a stimulus at a given position in retinal space, and the gain modulation signals needed are eye position, head direction, and place, all of which are present in the primate brain. Neurons that encode the bearing to a landmark are involved in the coordinate transforms. Part of the importance here is that the coordinates of the allocentric view produced in this model are the same as those of spatial view cells that respond to allocentric view recorded in the primate hippocampus and parahippocampal cortex. The result is that information from the dorsal visual system can be used to update the spatial input to the hippocampus in the appropriate allocentric coordinate frame, including providing for idiothetic update to allow for self‐motion. It is further shown how hippocampal spatial view cells could be useful for the transform from hippocampal allocentric coordinates to egocentric coordinates useful for actions in space and for navigation.

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Effects of Chemotherapy on the Immune System: Implications for Cancer Treatment and Patient Outcomes

Sharma,

Jasrotia,

Kumar

2023

Naunyn-Schmiedeberg's Arch Pharmacol

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L’orientation spatiale chez le primate

Cited by 4 publications

References 13 publications

Spatial representations in the primate hippocampus, and their functions in memory and navigation

Spatial representations in the primate hippocampus, and their functions in memory and navigation

Spatial coordinate transforms linking the allocentric hippocampal and egocentric parietal primate brain systems for memory, action in space, and navigation

Effects of Chemotherapy on the Immune System: Implications for Cancer Treatment and Patient Outcomes

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