L‐kynurenine and quinolinic acid inhibited markers of cell survival in B16 F10 melanoma cells in vitro
Charlise Basson,
June Cheptoo Serem,
Priyesh Bipath
et al.
Abstract:Melanoma is an aggressive malignancy and remains a major cause of skin cancer mortality, highlighting the need for new treatment strategies. Recent findings revealed that L‐kynurenine and quinolinic acid induce cytotoxicity and morphological changes in B16 F10 melanoma cells in vitro. This paper highlights the effects of
L‐kynurenine and quinolinic acid at previously determined half‐maximal inhibitory concentrations on cell cycle progression, cell death and extracellular signal‐regulated protein kinase inhibi… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.