L’état de stress post-traumatique comme conséquence de l’interaction entre une susceptibilité génétique individuelle, un évènement traumatogène et un contexte social

Auxéméry, Yann

doi:10.1016/j.encep.2011.12.003

Cited by 86 publications

(21 citation statements)

References 29 publications

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“…The effects of childhood trauma on later vulnerability to stress and disease are also moderated by genotype [46]. The serotonin transporter gene 5 HTTLPR significantly moderates the effects of stressful life events on depression.…”

Section: Neurobiological Factors That Link Childhood Trauma To Adumentioning

confidence: 99%

Depression and Psychological Trauma: An Overview Integrating Current Research and Specific Evidence of Studies in the Treatment of Depression in Public Mental Health Services in Chile

Vitriol

Cancino

Weil

et al. 2014

Depression Research and Treatment

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In the last two decades, different research has demonstrated the high prevalence of childhood trauma, including sexual abuse, among depressive women. These findings are associated with a complex, severe, and chronic psychopathology. This can be explained considering the neurobiological changes secondary to early trauma that can provoke a neuroendocrine failure to compensate in response to challenge. It suggests the existence of a distinguishable clinical-neurobiological subtype of depression as a function of childhood trauma that requires specific treatments. Among women with depression and early trauma receiving treatment in a public mental health service in Chile, it was demonstrated that a brief outpatient intervention (that screened for and focused on childhood trauma and helped patients to understand current psychosocial difficulties as a repetition of past trauma) was effective in reducing psychiatric symptoms and improving interpersonal relationships. However, in this population, this intervention did not prevent posttraumatic stress disorder secondary to the extreme earthquake that occurred in February 2010. Therefore in adults with depression and early trauma, it is necessary to evaluate prolonged multimodal treatments that integrate pharmacotherapy, social support, and interpersonal psychotherapies with trauma focused interventions (specific interventions for specific traumas).

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Section: Neurobiological Factors That Link Childhood Trauma To Adumentioning

confidence: 99%

Depression and Psychological Trauma: An Overview Integrating Current Research and Specific Evidence of Studies in the Treatment of Depression in Public Mental Health Services in Chile

Vitriol

Cancino

Weil

et al. 2014

Depression Research and Treatment

View full text Add to dashboard Cite

show abstract

“…A study on United States veterans from Afghanistan/Iraq era suggested that veterans with PTSD symptoms might have difficulty in accepting or benefitting from social support[32]. Moreover, some studies indicated that social support correlates with recovery from PTSD symptoms [33–34]. Given the collectivist culture in China, social support may be relevant to the outcomes in that social support is particularly important to Chinese women.…”

Section: Introductionmentioning

confidence: 99%

Association between social support and post-traumatic stress disorder symptoms among Chinese patients with ovarian cancer: A multiple mediation model

et al. 2017

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Post-traumatic stress disorder (PTSD) symptoms can develop after person experiences one or more traumatic events. Little research, however, has been done on PTSD symptoms of patients with ovarian cancer. The present study aimed to estimate the prevalence of PTSD symptoms in patients with ovarian cancer in China; the effects of demographic and clinical variables on PTSD symptoms; multiple mediation roles in the association between social support and PTSD symptoms in patients with ovarian cancer in China. We collected demographic and clinical information of patients with ovarian cancer in the first and second hospitals of China Medical University between January 1, 2014 and December 31, 2015. Qualified patients were asked to complete the Posttraumatic Stress Disorder Checklist-Civilian Version (PCL-C), Duke-UNC Functional Social Support Questionnaire, Herth Hope Index (HHI), and Resilience Scale-14 (RS-14). 201 patients provided responses. We performed hierarchical linear regression to assess the correlation between social support and PTSD symptoms and bootstrapping to test the mediating role of hope and resilience as potential mediators. After controlling demographic and clinical characteristics, social support negatively correlated with PTSD symptoms (β = -0.406, P < 0.01). Social support explained 14.7% of the variance in PTSD symptoms. Hope and resilience explained 17.0% of the variance in PTSD symptoms. The proportion of the hope mediating effect was 43.37% for social support and the proportion of the resilience mediating effect was 10.64% for social support. Hope and resilience partly mediated the correlation between social support and PTSD symptoms despite accounting for different proportions of the mediating effect. Future intervention plans should pay more attention to social support as well as hope and resilience to prevent, relieve and treat PTSD symptoms.

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“…In acute stress disorder symptoms resolve within 1 month of the occurrence of the traumatic event, while in PTSD symptoms are present for more than 1 month afterwards [73]. PTSD is an interaction between a subject, a traumatogenic factor and a social context and is defined as intrusive re-experiencing of the trauma, avoiding traumatic reminders, and persistent physiological arousal [74].…”

Section: Acute Stress Disorder/posttraumatic Stress Disorder (Ptsd)mentioning

confidence: 99%

Anxiety Disorder in Children: Review

Al‐Biltagi¹

2016

J.Paedi.Care.Inol

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Anxiety is a biological warning mechanism with intense feelings of fear that prepares us for action. It should be differentiated from the normal fear response. Anxiety disorders are one of the most common psychiatric disorders in children and adolescents, but they often go undetected or untreated. Childhood anxiety may be underestimated due to various factors. The prevalence of anxiety in a community depends on many factors, including race, sex, type of the anxiety, and the adequacy of the epidemiological studies. The development of anxiety disorders in children and adolescents involves interplay between heritable factors, developmental factors, cognitive and learning factors, neurobiological factors including genetic, social and environmental factors. Anxiety disorders in children and adolescents are often associated with other psychiatric disorders including other anxiety disorders, depression, attention-deficit hyperactivity disorder (ADHD), oppositional defiant disorder, substance abuse, and other psychiatric disorders. Management of anxiety disorders in children needs and integrative teamwork including cognitive behavioral therapy, mindfulnessbased psychotherapies, psychodynamic psychotherapies, and psychopharmacologic treatments.

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L’état de stress post-traumatique comme conséquence de l’interaction entre une susceptibilité génétique individuelle, un évènement traumatogène et un contexte social

Cited by 86 publications

References 29 publications

Depression and Psychological Trauma: An Overview Integrating Current Research and Specific Evidence of Studies in the Treatment of Depression in Public Mental Health Services in Chile

Depression and Psychological Trauma: An Overview Integrating Current Research and Specific Evidence of Studies in the Treatment of Depression in Public Mental Health Services in Chile

Association between social support and post-traumatic stress disorder symptoms among Chinese patients with ovarian cancer: A multiple mediation model

Anxiety Disorder in Children: Review

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