L-Asparginase Induced Pseudopancreatic Cyst: A Rare Case Report

Abstract

L-Asparginase is a frequently used drug in hematological malignancies. Various side effects associated with its use include hypersensitivity, hyperglycemia, hypercoaguability and acute pancreatitis. We describe a rare complication of pancreatic pseudocyst in a 12 year old boy of Acute lymphoblastic leukemia (ALL) treated with MCP-841 protocol (during re-induction phase). Nearing the end of induction i.e. day 25, patient complained of a painful swelling in the epigastrium and left hypochondrium. Investigations revealed a pancreatic pseudocyst for which he underwent cystojejunostomy. Post surgical period was uneventful.

An Unusual Case of Gallbladder Carcinoma with Pseudopancreatic cyst

“…Trauma is the most common cause of pancreatic pseudocysts in children. 17 Acute pancreatitis leads to necrosis of peri-pancreatic tissue or parenchyma which can cause liquefaction and subsequent organization resulting in pseudocysts. 18 Chronic pancreatitis leads to an acute exacerbation of pancreatitis or progressive ductal obstruction which can also lead to pseudocyst formation.…”