“…Stay-C is a stable form of vitamin C and has similar bioavailability to ascorbic acid in cats according to a study conducted by the supplier. Similar results have been reported in weaning pigs (De Rodas et al, 1998), sheep (Hidiroglou et al, 1997), sea bass, channel cat¢sh, calves, horses and dogs (Schulze et al, 1993). Ascorbic acid is a nonessential nutrient for cats.…”
Oxidative stress may contribute to the progression of chronic renal failure. In this study, cats with spontaneous renal insufficiency were fed a dry cat food supplemented with the antioxidants vitamins E and C, and beta-carotene for 4 weeks. When compared with healthy cats, cats with renal insufficiency had a tendency to oxidative stress. The antioxidant supplements significantly reduced DNA damage in cats with renal insufficiency as evidenced by reduced serum 8-OHdG and comet assay parameters. Therefore, supplements of vitamins E and C and beta-carotene as antioxidants may be beneficial to cats with renal disease.
“…Stay-C is a stable form of vitamin C and has similar bioavailability to ascorbic acid in cats according to a study conducted by the supplier. Similar results have been reported in weaning pigs (De Rodas et al, 1998), sheep (Hidiroglou et al, 1997), sea bass, channel cat¢sh, calves, horses and dogs (Schulze et al, 1993). Ascorbic acid is a nonessential nutrient for cats.…”
Oxidative stress may contribute to the progression of chronic renal failure. In this study, cats with spontaneous renal insufficiency were fed a dry cat food supplemented with the antioxidants vitamins E and C, and beta-carotene for 4 weeks. When compared with healthy cats, cats with renal insufficiency had a tendency to oxidative stress. The antioxidant supplements significantly reduced DNA damage in cats with renal insufficiency as evidenced by reduced serum 8-OHdG and comet assay parameters. Therefore, supplements of vitamins E and C and beta-carotene as antioxidants may be beneficial to cats with renal disease.
“…Most of the experiments reviewed concerned weanling and growing swine. Vitamin C supplementation seems to be beneficial for enhancing growth and performance of weaned pigs, particularly at a very young age (de Rodas et al, 1998;Mahan and Saif, 1983;Yen and Pond, 1981). Furthermore, studies on swine have shown that vitamin C supplementation had no positive effect on bone metabolism (Pointillart et al, 1997), nor did it affect blood hemoglobin and hematocrit levels (de Rodas et al, 1998;Mahan and Saif, 1983).…”
“…Harlan-Teklad modified their basic vitamin C-deficient guinea pig diet (TD 93061) by adding L L-ascorbyl-2-polyphosphate (''Stay-C 35'') at levels of 50, 500, and 5000 mg/kg food to create ''deficient'', ''normal'', and ''supplemented'' diets, respectively. Because vitamin C is innately unstable and can be readily oxidized when exposed to oxygen or certain minerals, stabilized forms of vitamin C such as L L-ascorbyl-2-polyphosphate are recommended over L L-ascorbic acid for animal diets (de Rodas et al, 1998). Harlan-Teklad has used L L-ascorbyl-2-polyphosphate instead of coated ascorbic acid in their standard primate and guinea pig diets for several years, because of its increased stability during the manufacturing process and prolonged shelf life under various storage conditions (Barb Mickelson, personal communication).…”
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