L. Acidophilus in patients with mental disease

Kopeloff, Nicholas; Blackman, Nathan; McGinn, B.

doi:10.1007/bf01583942

Cited by 2 publications

(1 citation statement)

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“…In three small published case series, acidophilus milk was reported to improve constipation and diarrhea, but not behavioral or mental status of patients, at least not in those with more serious forms of mental illness such as schizophrenia [102-104]. Moreover, researchers from New York were unable to detect differences in the presence or absence of L. acidophilus in the stool of 187 patients with a variety of mental health disorders vs. controls (although they did not quantify the L. acidophilus levels, reporting merely whether or not it was present at all) [105]. …”

Section: Series Introductionmentioning

confidence: 99%

Intestinal microbiota, probiotics and mental health: from Metchnikoff to modern advances: Part I – autointoxication revisited

2013

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Mental health disorders, depression in particular, have been described as a global epidemic. Research suggests that a variety of lifestyle and environmental changes may be driving at least some portion of the increased prevalence. One area of flourishing research involves the relationship between the intestinal microbiota (as well as the related functional integrity of the gastrointestinal tract) and mental health. In order to appreciate the recent scientific gains in this area, and its potential future directions, it is critical to review the history of the topic. Probiotic administration (e.g. Lactobacillus) and fecal microbiota transfer for conditions associated with depression and anxiety is not a new concept. Here, in the first of a 3-part series, we begin by reviewing the origins of the contemporary research, providing a critical appraisal of what has become a revisionist history of the controversial term ‘autointoxication’. We argue that legitimate interests in the gut-brain-microbiota connection were obscured for decades by its association with a narrow historical legacy. Historical perspectives provide a very meaningful context to the current state of the contemporary research as outlined in parts II and III.

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Section: Series Introductionmentioning

confidence: 99%