“…The stereotyped complex spike consists of a fast, prominent first spike followed by two to six smaller, high-frequency spikelets. PCs possess multiple intrinsic somatic and dendritic conductances that may interact with synaptic inputs to sculpt membrane voltage signals (Llinas and Sugimori, 1980a,b;Raman and Bean, 1997;Womack and Khodakhah, 2002;Swensen and Bean, 2003;McKay and Turner, 2004;Khavandgar et al, 2005). However, discrepancies remain regarding the ionic mechanisms responsible for the generation of the complex spike, including whether spikelets are generated at somatic or dendritic membranes and, more generally, the importance of somatic versus dendritic excitability to the somatic complex spike waveform (Callaway et al, 1995;Callaway and Ross, 1997;Hansel and Linden, 2000;Schmolesky et al, 2002;Weber et al, 2003;Davie and Hausser, 2004).…”