Kutane amerikanische Leishmaniose

Bormann, Gisela; William, Thomas; Schulz, Anselm; Marsch, Wolfgang Ch.; Gaber, G.

doi:10.1055/s-2003-42703

Dtsch med Wochenschr

2003

DOI: 10.1055/s-2003-42703

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Kutane amerikanische Leishmaniose

Gisela Bormann

Thomas William²,

Anselm Schulz³

et al.

Abstract: The diagnosis of American cutaneous Leishmaniasis may be complicated by the relative lack of pathogens in the lesions. PCR diagnosis are very helpful here. The therapy must be systemic owing to the danger of progression to mucocutaneous Leishmaniasis. The standard therapeutic pentostam has, however, a high rate of side effects and administration is exclusively intravenous.

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Cited by 2 publications

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Nasal mucocutaneous leishmaniasis (MCL) with necrotizing granulomatous inflammation inducing cytotoxic T-cell lymphoma in a male Yemeni patient

Ibrahim,

Hamid,

Aziz

et al. 2023

Egypt J Intern Med

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Leishmaniasis is a protozoal infection transmitted by sandfly vector; there are three main types of leishmaniasis: cutaneous leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), and visceral leishmaniasis (VL). Herein, we present a case of endonasal mucocutaneous leishmaniasis in a 34-year-old Yemeni patient who presented with disfiguring nasal swelling associated with fever, a swab from the lesion and direct microscopic examination proved to have mucocutaneous leishmaniasis; he was successfully treated with intravenous antimonial stibogluconate, 1 month after treatment biopsy from the lesion revealed cytotoxic T-cell lymphoma, the purpose is to alert the physicians and otolaryngologists to consider leishmaniasis in the differential diagnosis of nasal granulomas and also to highlight the importance of early diagnosis of cancer in survivors of cutaneous leishmaniasis, especially in areas where cutaneous leishmaniasis is still highly prevalent, as the chronic local inflammation may disfigure the face if not recognized early and adequately treated; also, early cancer diagnosis can prevent mortality

show abstract

Nasal mucocutaneous leishmaniasis (MCL) with necrotizing granulomatous inflammation inducing cytotoxic T-cell lymphoma in a male Yemeni patient

Ibrahim,

Hamid,

Aziz

et al. 2023

Egypt J Intern Med

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Non-Endemic Leishmaniases Reported Globally in Humans between 2000 and 2021—A Comprehensive Review

Rocha¹,

Pereira

Maia³

2022

Pathogens

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Leishmaniases are human and animal parasitic diseases transmitted by phlebotomine sand flies. Globalization is an important driver of the burden and in the current dynamics of these diseases. A systematic review of articles published between 2000 and 2021 was conducted using the PubMed search engine to identify the epidemiology and clinical management of imported human leishmaniases as a fundamental step to better manage individual cases and traveler and migrant health from a global perspective. A total of 275 articles were selected, representing 10,341 human imported cases. Identified drivers of changing patterns in epidemiology include conflict and war, as well as host factors, such as immunosuppression, natural and iatrogenic. Leishmania species diversity associated with different clinical presentations implies diagnostic and treatment strategies often complex to select and apply, especially in non-endemic settings. Thus, diagnostic and management algorithms for medical clinical decision support are proposed. Increased surveillance of non-endemic cases, whether in vulnerable populations such as refugees/migrants and immunocompromised individuals or travelers, could improve individual health and mitigate the public health risk of introducing Leishmania species into new areas.

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Kutane amerikanische Leishmaniose

Cited by 2 publications

References 11 publications

Nasal mucocutaneous leishmaniasis (MCL) with necrotizing granulomatous inflammation inducing cytotoxic T-cell lymphoma in a male Yemeni patient

Nasal mucocutaneous leishmaniasis (MCL) with necrotizing granulomatous inflammation inducing cytotoxic T-cell lymphoma in a male Yemeni patient

Non-Endemic Leishmaniases Reported Globally in Humans between 2000 and 2021—A Comprehensive Review

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