2013
DOI: 10.3324/haematol.2012.066944
|View full text |Cite
|
Sign up to set email alerts
|

Kruppel-like factor 4 blocks tumor cell proliferation and promotes drug resistance in multiple myeloma

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

2
25
0

Year Published

2014
2014
2019
2019

Publication Types

Select...
7

Relationship

0
7

Authors

Journals

citations
Cited by 25 publications
(27 citation statements)
references
References 46 publications
2
25
0
Order By: Relevance
“…Attenuation of KLF-4 expression promotes carcinogenesis by inducing G1/S phase arrest in clear cell renal cell carcinoma (Song et al, 2013). KLF-4 blocks tumor cell proliferation and promotes drug resistance in multiple myeloma (Schoenhals et al, 2013). In the present study, we investigated the regulatory role of KLF-4 in the proliferation of CRC HT-29 cells by abrogating KLF-4 expression.…”
Section: Discussionmentioning
confidence: 96%
“…Attenuation of KLF-4 expression promotes carcinogenesis by inducing G1/S phase arrest in clear cell renal cell carcinoma (Song et al, 2013). KLF-4 blocks tumor cell proliferation and promotes drug resistance in multiple myeloma (Schoenhals et al, 2013). In the present study, we investigated the regulatory role of KLF-4 in the proliferation of CRC HT-29 cells by abrogating KLF-4 expression.…”
Section: Discussionmentioning
confidence: 96%
“…Transducing in vitro generated PBs with a control measles lentivirus did not change EPC counts as previously indicated (results not shown). 18 This increase in EPC counts by a forced KLF4 expression is the result of combined increases in cell survival (from 48% in control EPCs to 65% in KLF4 C EPCs, P D .004, Fig. 2B) and in the efficacy of the differentiation of PBs into EPCs (from 49% CD138 C EPCs in the control group to 57% CD138 C EPCs in the KLF4 group, P D .02, Fig.…”
Section: Resultsmentioning
confidence: 99%
“…20 Measles envelop pseudotyped lentiviruses were used because they can transduce human PCs unlike vsv-g envelop pseudotyped ones 18 (Fig. 1B).…”
Section: Resultsmentioning
confidence: 99%
See 2 more Smart Citations