Kosteneffektivität der Prophylaxe und Behandlung von Influenza

Rychlik, Reinhard; Heinen-Kammerer, Tatjana; Rusche, Herbert; Piercy, James; Scuffham, Paul Anthony; Zöllner, York

doi:10.1055/s-2003-43100

Cited by 7 publications

(2 citation statements)

References 4 publications

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“…Vaccination has been shown to be the most cost-effective intervention in preventing infection and subsequently reducing the associated financial burden [ 6 , 7 ]. Safe and effective influenza vaccines prevent 44–73 % of influenza symptoms among healthy adults [ 8 ] and reduce deaths by 80 % in the elderly [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

Cost for physician-diagnosed influenza and influenza-like illnesses on primary care level in Germany – results of a database analysis from May 2010 to April 2012

Ehlken¹,

Anastassopoulou

Hain

et al. 2015

BMC Public Health

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BackgroundSeasonal influenza is one of the most significant infectious diseases in Germany; epidemic outbreaks occur every winter and cause substantial morbidity and mortality. However, published data from Germany on the current economic burden of influenza and the costs per episode are lacking.MethodsA retrospective database analysis was conducted using a longitudinal electronic medical records database (IMS Disease Analyzer). Patients with influenza, diagnosed by German office-based physicians using ICD-10 J09-11 (International Classification of Diseases, 10th revision), who were observable in the database from 12 months before the index (diagnosis) date until 1 month afterwards, were included. The selection window, defined to cover two influenza seasons, was May 2010 to April 2012. Direct and indirect costs were evaluated from payer, patient and societal perspectives. Published unit costs and tariffs from Germany (2012) were used for the analysis.ResultsA total of 21,039 influenza-attributable episodes in 17,836 adults, managed by primary care physicians (PCP) and 7,107 episodes in 6,288 children, managed by pediatricians, were eligible for analysis. The mean (±Standard Deviation (SD)) age of the adults with at least one episode was 46 (±18) years and 7 (±4) years in the children. The presence of clinical risk factors was documented for 39 % episodes in adults and 24 % episodes in children, with the most common being cardiovascular diseases in adults (29 %) and chronic respiratory diseases in children (23 %). Complications and severe symptoms accompanied the influenza-attributable episode (adults: 37 %, children: 54 %), bronchitis (adults: 16 %, children: 19 %) and acute upper respiratory infection (adults: 15 %, children: 21 %) being the most frequent. From a societal perspective, the total average mean cost (±SD) per episode was €514 (±609) in adults, where work days lost were the main cost driver (82 %), and €105 (±224) in children. Complications and severe symptoms increased the cost per episode versus episodes without by 1.7 times in adults (€684 (±713) vs. €413 (±510)) and nearly 3 times in children (€149 (±278) vs. €55 (±116)).ConclusionsBased on a large patient sample derived from representative PCP and pediatricians panels, our results demonstrate that seasonal influenza is associated with substantial clinical and economic burden in Germany.Electronic supplementary materialThe online version of this article (doi:10.1186/s12889-015-1885-0) contains supplementary material, which is available to authorized users.

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Section: Introductionmentioning

confidence: 99%

Cost for physician-diagnosed influenza and influenza-like illnesses on primary care level in Germany – results of a database analysis from May 2010 to April 2012

Ehlken¹,

Anastassopoulou

Hain

et al. 2015

BMC Public Health

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“…In addition to containing or eliminating infectious agents, vaccination also saves costs2,3, which is particularly important in this era of low worldwide funding for health issues. The Nichol study group at the Veteran Affairs Medical Center (Minneapolis, MN, USA), determined that for every elderly person who is vaccinated against influenza, 42.9 US dollars is saved 4…”

Section: Introductionmentioning

confidence: 99%

The provision of pharmaceutical advice improves patient vaccination status

Fuchs

2006

Pharmacy pract. (Granada Ed. impr.)

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AimTo increase vaccination rates in the wealthy industrial nation of Germany. For a variety of reasons there is a substantial deficit in the number of individuals who receive vaccinations in comparison with other industrialized countries.MethodsIn Autumn 2003, a regional vaccination consultation was initiated over a five-week period. Individuals involved in the study provided general information, including their age, health status, and vaccination records, and received an extensive consultation in a pharmacy in Jena, Germany. Participants were provided with a written overview of their vaccination status. After approximately five weeks, the vaccination status of each individual was recorded.Results312 of 2500 patients received intensive vaccination education based on their accompanying vaccination documentation. Older individuals, who are known for having the largest vaccination gap in Germany, represented the highest percentage of people who used this service. The five most commonly required vaccinations had increased significantly, five weeks after the consultation. These vaccination rate increases included diphtheria, which rose from 55.8 to 71.2%, tetanus, which rose from 73.1 to 86.5%, influenza, which rose from 46.5 to 74.7%, pneumococcal, which rose from 32.4 to 62.8%, and tick-borne encephalitis, which rose from 31.9 to 42.4% (all p<0.008).ConclusionsWell structured vaccination consultations help to raise vaccination rates. Thus, pharmacies should consider offering and implementing this preventive measure so as to lower the rates of preventable disease and to save costs.

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Die Prävention psychischer Erkrankungen und die Förderung psychischer Gesundheit

Kilian¹,

Becker²

Prävention

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Kosteneffektivität der Prophylaxe und Behandlung von Influenza

Cited by 7 publications

References 4 publications

Cost for physician-diagnosed influenza and influenza-like illnesses on primary care level in Germany – results of a database analysis from May 2010 to April 2012

Cost for physician-diagnosed influenza and influenza-like illnesses on primary care level in Germany – results of a database analysis from May 2010 to April 2012

The provision of pharmaceutical advice improves patient vaccination status

Die Prävention psychischer Erkrankungen und die Förderung psychischer Gesundheit

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