1969
DOI: 10.1055/s-0028-1110315
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Korrelation des laparoskopischen und histologischen Befundes bei chronischer Hepatitis und Leberzirrhose

Abstract: Korrelation des laparoskopischen und histologischen Befundes bei chronischer Hepatitis und Leberzirrhose Seit der Einführung der Laparoskopie und Leberbiopsie in die routinemäßig angewandten Untersuchungsmethoden wird bei Leberkranken der morphologische Befund als diagnostisches Hauptkriterium angesehen. Die biochemischen Befunde, die bis zu dieser Zeit im Vordergrund der Leberdiagnostik standen, informieren heute nur noch über die Funktion der Leber und teilweise über die Aktivität der Entzündung, aber auch d… Show more

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Cited by 41 publications
(8 citation statements)
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“…Since our findings could not be controlled by postmortem examination except in 16 cases (10 %), the percentage of false-negative results of the two methods remains unknown. As far as we know the only studies comparing peritoneoscopy and liver biopsy have been those of Vido and Wildhirt (1969), Fritsch, Herms, Huth, Wetzels, and Hausamen (1972) and Gros (1973). In these reports no false-negative findings of peritoneoscopy are given since the selection of patients was made only by endoscopic criteria, and the accuracy of liver biopsy was surprisingly low.…”
Section: Discussionmentioning
confidence: 99%
“…Since our findings could not be controlled by postmortem examination except in 16 cases (10 %), the percentage of false-negative results of the two methods remains unknown. As far as we know the only studies comparing peritoneoscopy and liver biopsy have been those of Vido and Wildhirt (1969), Fritsch, Herms, Huth, Wetzels, and Hausamen (1972) and Gros (1973). In these reports no false-negative findings of peritoneoscopy are given since the selection of patients was made only by endoscopic criteria, and the accuracy of liver biopsy was surprisingly low.…”
Section: Discussionmentioning
confidence: 99%
“…Presently, there are no reliable non-invasive investigations predictive of cirrhosis and the presence or absence of cirrhosis must be assessed by liver biopsy, a procedure associated with significant morbidity and mortality [33]. Furthermore, the diagnosis of cirrhosis using only a liver biopsy may be missed in 1-60% of cases [34][35][36] (therefore in this study, the diagnosis of cirrhosis was made by a combination of laparoscopy and liver biopsy). Long-term follow-up of patients with chronic hepatitis C also requires serial liver biopsies to reassess repeatedly the hepatic histology.…”
Section: Discussionmentioning
confidence: 99%
“…rhosis [8]. In contrast, rates of false-negative findings in the diagnosis of cirrhosis are estimated to be 4-18 % in laparoscopy [4, 9 -12].…”
Section: Original Articlementioning
confidence: 99%
“…The diagnosis of complete cirrhosis required unequivocal and complete nodularity of the liver with macroscopically visible and completely separating fibrous septations. Incomplete cirrhosis was diagnosed when nontumorous nodularity was present, but separation by fibrous septations was not unequivocally complete [8]. Based on the predominant size of the nodules, cirrhosis was further classified as micronodular (nodules < 3 mm), nodular (nodules 3 -7 mm), or macronodular (nodules > 7 mm), according to the macroscopic evaluation defined by previous clinical observations of Vido & Wildhirt and Henning [8,16].…”
Section: Macroscopic Evaluation Of Cirrhosismentioning
confidence: 99%