Korean red ginseng formula attenuates non-alcoholic fatty liver disease in oleic acid-induced HepG2 cells and high-fat diet-induced rats

Zheng, Min; Yang, Li; Dong, Zhiying; Zhang, Yibo; Xi, Zhichao; Yuan, Man; Xu, Hong‐Xi

doi:10.1016/j.heliyon.2023.e21846

“…Further, other related genes such as cebpa, srebf1, acaca, and hmgcr levels were also increased in the liver of HF diet-fed rats, which was further normalized by purple potato extract treatment. This finding is also supported by the previous report showing that the Korean red ginseng formula decreased the expression of lipogenesis factors, namely cebpa, srebf1 and acaca in rats [ 64 ].…”

Section: Discussionsupporting

confidence: 89%

Purple potato extract modulates fat metabolizing genes expression, prevents oxidative stress, hepatic steatosis, and attenuates high-fat diet-induced obesity in male rats

Jahan

¹

,

Shuvo

²

,

Alimullah

³

et al. 2025

PLoS ONE

0

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

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“…The observe reduction in fat droplets with RG treatment suggests a protective effect against hepatic steatosis, which may help maintain liver function during aging. This efficacy of RG in reducing hepatic fat droplets was also observed in another study using high-fat diet-induced rats [ 47 ]. Thus, RG demonstrates potential in preserving both liver function and structure during aging, possibly by modulating liver biomarkers and reducing hepatic steatosis.…”

Section: Discussionsupporting

confidence: 71%

Effects of Korean red ginseng on auditory, cognitive, and liver functions in a naturally aged mouse model

Shin

¹

,

Shim

²

,

Nam

³

et al. 2025

Journal of Ginseng Research

1

0

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…Phytochemical analyses and clinical observations reveal that Monascus -fermented rice (Hongqu) mediates marked reductions in total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C), establishing its therapeutic candidacy for statin-intolerant patients exhibiting statin-associated myopathy or hepatotoxicity [ 7 ]. Furthermore, a series of studies have demonstrated that poria [ 8 ], ginseng [ 9 ], magnolia [ 10 ], Pericarpium Citri reticulatae [ 11 ], gynostemma [ 12 ], Rhizoma Polygonati odorati [ 13 ], cassia seed [ 14 ], etc., have excellent therapeutic effects on HLP. Microbial fermentation has been recognized in TCM since ancient times for its potential to enhance the quality of the medicinal substances present in the aforementioned medicinal plants.…”

Section: Introductionmentioning

confidence: 99%

Gut Microbiota-Targeted Intervention of Hyperlipidemia Using Monascus-Fermented Ginseng

Zhou

¹

,

Yang

²

,

Jia

³

et al. 2025

Pharmaceuticals

0

Get access via publisher Add to dashboard Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

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Korean red ginseng formula attenuates non-alcoholic fatty liver disease in oleic acid-induced HepG2 cells and high-fat diet-induced rats

Cited by 6 publications

References 40 publications

Purple potato extract modulates fat metabolizing genes expression, prevents oxidative stress, hepatic steatosis, and attenuates high-fat diet-induced obesity in male rats

Purple potato extract modulates fat metabolizing genes expression, prevents oxidative stress, hepatic steatosis, and attenuates high-fat diet-induced obesity in male rats

Effects of Korean red ginseng on auditory, cognitive, and liver functions in a naturally aged mouse model

Gut Microbiota-Targeted Intervention of Hyperlipidemia Using Monascus-Fermented Ginseng

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